Aetna considers CEA-Scan® using Tc-99m-arcitumomab, a radiodiagnostic agent produced by Immunomedics, for use in conjunction with computerized tomography (CT) scans medically necessary for detection of recurrent or metastatic colorectal cancer in the liver and extra-hepatic abdomen and pelvis. ...
As a form of inflammatory cell death (ICD), pyroptosis has the potential to transform the immune "cold" tumors into "hot" tumors by releasing proinflammatory factors and reshaping immune cells within the TME [88]. One of the distinctive features of pyroptosis is the release of inflammatory cyto...
For patients with ovarian cancer, chemo-resistant cells can develop into multi-cellular spheroids and spread via ascites that accumulate in their abdomen. These spheroids consist of 3D structures that are highly heterogeneous with different shapes, sizes, and compositions of cell types. Therefore, ...
In one study, mice subjected to whole abdomen radiation through timed exposure to X-rays at a cumulative dose exhibited heightened levels of p-TBK1 and p-IRF3 in colonic tissues, along with increased IFN-β levels following NLRP3 deficiency. The absence of NLRP3 resulted in elevated cGAS-...
Water administered by stomach tube at 10–15 mL/kg will enhance visibility of mural pathology. The hair should be clipped from the cranial ventral abdomen, between the xiphisternum and the umbilicus, the skin cleaned with surgical spirit and liberal quantities of acoustic gel applied. The ...
CT scan of abdomen and pelvis every 6 mo for 2 yr in addition to chest x-ray examination, liver function tests, and serum creatinine. • Loopogram every 6 mo for 2 yr, then yearly. PEARLS & CONSIDERATIONS COMMENTS • The most useful prognostic parameters for bladder tumor recurrence and...
As discussed in the introduction, BFO-triggered and glycosylation inhibition-enhanced piezocatalytic tumor immunotherapy is expected to provide a “hot” tumor immune niche by inducing the ICD of tumor cells. Therefore, the performance of different therapeutic approaches to induce ICD of tumors was firs...
When used for the treatment of CT26 peritoneal metastatic tumors, DOX and anti-PD-1 maintained a relatively high concentration in the abdomen of mice, with gradual degradation of the implants occurring in the abdominal cavity. This led to obvious synergistic effects of immunogenic chemotherapy and ...
5 Chest x-ray shows left pleural effusion with superinfection before drainage (left) after drainage (right) Differential diagnosis To look for the cause of pulmonary embolism an exten- sive workup was carried out with computed tomogra- phy (CT) of the abdomen, pelvis and brain showing...
Repair of a large incisional hernia in the lower abdomen with tow piece of Merlex graft. A patient complains of chest pain and a myocardial infarction is suspected. Which of the following tests or procedures would not provide information to support the diagnosis of...