Advances in techniques of testing mycobacterial drug sensitivity, and the use of sensitivity tests in tuberculosis control programmes. Bull World Health Organ 1969; 41: 21–43. 46 Zaunbrecher MA, Sikes RD Jr, Metchock B, et al. Overexpression of the chromosomally encoded aminoglycoside ...
Liver function tests showed indications of obstructive jaundice and hepatic dysfunction. He rapidly deteriorated and died 3 days after admission. Autopsy revealed disseminated miliary tuberculosis in all major organs. Many miliary tubercles were densely distributed in the liver, especially in and near ...
accuracy. Since they are not capable of combining B-cell and T-cell predictions at a time, it is necessary to develop better models that will ease the tedious process of selecting B-cell and T-cell epitopes for building the vaccine. The contributions of this proposed method are: This study...
was used to infer drug resistance profiles in silico from known drug resistance mutations. assuming the drug susceptibility tests as the reference standard, the computationally inferred resistance profiles were highly accurate for rmp (sensitivity/specificity: 0.962/1.000) and inh (0.908/0.935), ...
Selection of SNPs in the 3q23 locus was conducted based on information from the dbSNP database (http://www.ncbi.nlm.nih.gov/projects/SNP/). Four polymorphisms rs73226617, rs73226619, rs73239724, and rs73226608 were included for the genotyping tests. Real-time PCR using the following calculat...
Also, 3.21% of case-patients who did not undergo the AFB test used other diagnostic tests such as Xpert (Xpert MTB/RIF by Cepheid, California, United States), which initiates TB treatment. The strength of this study was that it was the first to measure the impact of TB mobile teams in...
a because infected persons may not have any symptoms, all pregnant women should be tested for hbsag. if the mother tests positive, her newborn needs hepatitis b immune globulin to provide passive immunity and thus prevent infection. in addition, the newborn is given the hepatitis b...
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A. et al. Outbreak of multidrug-resistant tuberculosis in South Africa undetected by WHO-endorsed commercial tests: an observational study. Lancet Infect. Dis. 18, 1350–1359 (2018). PubMed Google Scholar Tagliani, E. et al. Culture and next-generation sequencing-based drug susceptibility ...
With mycobacterial culture as the reference standard, MTB/RIF tests when done on two induced sputum samples detected twice as many cases (75·9%, 95% CI 64·5–87·2) as did smear microscopy (37·9%, 25·1–50·8), detecting all of 22 smear-positive cases and 22 of 36 (61·1%,...