Tuberculosis Concept Map Advanced Pathophysiology University of CincinnatiCenter for Disease Control and Prevention (CDC, 2010) | Your Online source for credible health information. Retrieved from: http://www.cdc.gov/tb Center for Disease Control and Prevention (CDC, ...
Pathophysiology of Tuberculosis Exposure to tuberculosis occurs by inhalation of droplets containing live organisms. Because of their small size, the organisms are usually deposited in the distal areas of the lung. In the first stage of the disease, mycobacteria take up residence in phagosomes within...
The goal of this article is to discuss the basic pathophysiology of TB infection and disease, means of spread of TB, risk factors associated with TB, signs and symptoms of TB and basic nursing care of patients with TB, emphasizing the care that patients with both renal disease and TB ...
The understanding of LTBI has gone through 3 phases: the period of gross anatomy, the period of pathology, and the period of immunology [13]. Nowadays, LTBI refers to a condition where an individual has been infected with MTB but does not exhibit any symptoms or signs of active disease. M...
we depicted a global TB-associated splicing profile, developed TB-related AS biomarkers, demonstrated an optimal application scope of target biomarkers and preliminarily elucidatedmycobacterium tuberculosis-host interaction from the perspective of splicing, offering a novel insight into the pathophysiology of ...
c A high degree of lung damage in the external pathophysiology is observed 28 days post infection with H37Rv, ΔhisD and chisD in B6 MHC-II−/− null mice (pictures are representative of three individual mice lungs samples). d While un-stimulated macrophages show low titres of secreted ...
The PPE38 loss of function mutant thus lacks the secretion of PPE-MPTR and PE_PGRS proteins and surprisingly displays more virulent phenotypes (Ates et al., 2018a), thereby contributing to the enigmatic functions of these proteins in mycobacterial pathophysiology. Using slow-growing mycobacteria, M...
Individuals treated for multidrug-resistant tuberculosis (MDR-TB) with aminoglycosides (AGs) in resource-limited settings often experience permanent hearing loss. However, AG ototoxicity has never been conceptually integrated or causally linked to MDR-TB patients’ pre-treatment health condition. We sought...
In this article, we review the pathophysiology, clinical presentation, treatment, and management of HIV/TB coinfection during pregnancy, the postpartum period, and lactation and highlight the differences compared to the general population. Keywords: TB; HIV; coinfection; pregnancy; postpartum ...
In addition to miRNAs, one study showed that small nuclear RNA (snoRNA) and PIWI-interacting RNA (piRNA) are important biomarkers for TBI with potential participation in the TB pathophysiology [180]. Table 4. mRNAs and miRNAs that significantly differentiate ATB and TBI. A study by Zak et...