lung adenocarcinoma (ADC), non small cell lung cancer (NSCLC), epidermal growth factor receptor (EGFR), prognosis in thyroid transcription factor 1 negative (TTF1) adenocarcinoma.BACKGROUND: Patients with thyroid transcription factor 1 (TTF1) negative lung adenocarcinoma (ADC) have been reported to...
deathinducing, and dominantnegative activitiesMolecular Cell, 1998, 2 (3): 305316. [10] A It aner S, Yoruk Y, Toka tli F, et al The correlation between TTF1 immunoreactivity and the occurrence of lymph node metastases in patients with lung cancer. Tumori, ...
Weak TTF1 signals were found in two of four adenocarcinoma (AdC) cell lines, whereas two AdC cell lines and all squamous cell carcinoma (SqCC) and large-cell carcinoma (LaCC) cell lines examined were TTF1 negative. TTF1 isoform 2 was predominantly expressed in lung cancer cells. Recombinant...
There was a strong positive correlation between cMyc and the efficacy of NCB-0846 (r=-0.484, P<0.01), while a negative correlation between TTF1 and the efficacy (r=0.569, P<0.01). Additionally, NCB0846 decreased the expression of cMyc in cMyc-high/TTF-1 low SCLC cells.Conclusions: ...