因此,加强LTBI的筛查与干预,防止其进一步发展为活动性结核病对降低TB疫情意义重大。但目前全球尚缺乏既精确又廉价的结核感染鉴别技术。用于TB筛查的结核菌素皮肤试验(tuberculin skin test,TST) 易受卡介苗接种和非结核分枝杆菌(NTM)的影响而...
TB-IGRA:γ-干扰素释放试验(IGRA)原理是机体感染结核菌后产生结核菌抗原致敏的效应T细胞,致敏效应T细胞在体外再次受到相同抗原刺激后分泌大量的γ干扰素,通过检测γ干扰素判断结核感染情况。IGRA试验特异度与灵敏度均较高,试验快速简便,可作为是否存在结核感染的参考,但...
目前，全球TBST的3个产品Diaskintest（俄罗斯）和宜卡®（中国）已经上市，C-Tb（印度）尚未上市。据《柳叶刀·感染病学》的一项META分析显示：C-Tb的灵敏度为74.52%，Diaskintest的灵敏度为91.8%。而宜卡®的灵敏度为90.6%，后二者特异度相当。成诗明指出，应加强对高危人群和重点人群的结核潜伏感染筛和预防...
首先,指南延续了多年来对TST和IGRA的推荐。TST或γ-干扰素释放试验均可以(can be)用于TB感染检测。(强烈推荐) 其次,WHO第一次对基于结核分枝杆菌抗原的皮肤试验(TBST)进行了评估。为了评估TBST产品的可用性,WHO选取了全世界3个产品,Cy-Tb(印度)、Diaskintest(俄罗斯)及C-TST(中国)进行评价分析。 TBST 与 TST ...
tuberculin skin test (TST)tuberculosisvervet monkeyBackground Nowadays, several test methods with different useful values are available for diagnosis of the tuberculosis (TB) in non﹉uman primates (NHPs). Despite some limitations of tuberculin skin test (TST), it is still the most commonly used ...
评估中包括以下技术:C-Tb(印度血清研究所);C-TST(原名ESAT6-CFP10试剂,安徽智飞龙科马生物制药有限公司,中国)和Diaskinstest(俄罗斯Generium生物制药公司)。评估的目的是与TST和IGRA相比,TBST在患者中的主要结果、诊断准确性、安全性、一致性及经济学上和定性证据方面的优劣。这次快报旨在根据GDG的评估,向国家级结核...
ObjectiveTo explore the clinical application values of tuberculin skin test (TST) and interferon-γ release assays (IGRAs) in the differential diagnosis of pulmonary tuberculosis and pulmonary diseases other than tuberculous. MethodsThe data of IGRAs (T-SPOT.TB method) and TST test results of 603 ...
The tuberculin skin test (TST) is widely used in TB clinics to aid Mycobacterium tuberculosis (M.tb) diagnosis, but the definition and the significance of a positive test in very young children is still unclear. This study compared the TST in Gambian children at 4 months of age who either...
Recently, interferon-gammarelease assays (IGRAs) have been developed as a blood test forLTBI, providing an alternative to traditional tuberculin skintesting (TST). This cross sectional study sought to characterizeagreement between QuantiFERON®-TB Gold In-Tube (QFT) and TSTresults while ...
TSTTuberculin Skin Test TSTTime Sensitive Targeting TSTTaiwan Supercritical Technology TSTTractus Spinothalamicus TSTTest File TSTTwin Scroll Turbo TSTTouchless Sensor Technology TSTTwin Stage Turbo TSTTime Stamp Token TSTTemporary Storage Table TSTTransmission Simulation Task ...