Human anti-murine-immunoglobulin-antibodies (HAMA) were detected 2–3 weeks after treatment was started and reached maximal amounts of 0.8 μg/ml after a single and 2 μg/ml after a repeated treatment course. Parallely raised values of TSH were found in sera containing HAMAs of more than ...
ofthyroiddisease,andtreatmentofthyroiddisease. SUMMARYANDEXPLANATIONOFTHETEST Thyroidstimulatinghormone(TSH)orthyrotropinisaglycoproteinwitha molecularweightofapproximately28,000daltons,synthesizedbythe basophiliccells(thyrotropes)oftheanteriorpituitary. 1 TSHiscomposedof twonon-covalentlylinkedsubunitsdesignatedalphaand...