None of the 60 normal controls tested was found to carry any of the two mutations described above. DISCUSSION With the new mutation herein reported, a total of five mutations of the TSH ß-subunit gene have been identified as a cause of low TSH hypothyroidism worldwide. The G29R mutation...
Fig. 7. Shows fibrotic changes of the thyroid. In this condition recovery of thyroid morphology is not achievable. The central role that iron has in thyroid economy can be explained by one good reason: thyroid peroxidase is a hemeprotein. Heme is produced in mitochondria and the path into th...
As speculated above, this phenomenon might be explained by hypoxia due to placental insufficiency asso- ciated with more mature infants. Plasma AVP levels fell to normal within the first days of life (2,3,14), which may explain why first voiding was delayed over 24 h so infrequently, as ...
The highest bar plot represents the actual RP vs SP of the selected taxonomy level of miMic combined with the leaves test as explained in the Methods. Taxonomy levels used for the a priori nested ANOVA test are shaded in grey. The number of RPs significantly exceeds the number of SPs. B....
As speculated above, this phenomenon might be explained by hypoxia due to placental insufficiency asso- ciated with more mature infants. Plasma AVP levels fell to normal within the first days of life (2,3,14), which may explain why first voiding was delayed over 24 h so infrequently, as ...
It is not easy to check thyroid hormones levels in patients changed by the psychoactive process. It might be explained by the variety of clinical symptoms, heterogeneity of patients, smoking, unhealthy lifestyle, taking drugs or psychoactive substances, co-existence of cardiovascular pathology, etc....
It should be pointed out that in our study, the great majority of patients showed WC values above the cut-off, and the scarcity of values within the reference limits may have affected these results. Our findings could be explained by the hypothesis that obesity itself can play a role in au...