In contrast to the differentiated U87 cells where a relatively high AhR level is accompanied by a low Oct4 level (Fig. 1a,b), there appeared to be a positive correlation between them in U87 xenografts both at the mRNA and protein levels (Supplementary Fig. 38). The dramatic increase in ...
an expanded panel of human cancer cells was analysed, the correlation between thePOU5F1andAHRmRNA levels was still not obvious (Supplementary Fig. 2). The AhR protein levels in most examined cell lines correlated well with their mRNA levels (Fig. 1bversusFig. 1a), while the Oct4 protein ...
The photocoupling between BU and some of the aromatic amino acid peptide-like derivatives possibly mimics photocrosslinking of BU-DNA to associated proteins, a potentially useful photoreaction for studying nucleic acid-protein interactions. Formation of crosslinks of the type proposed here might be ...