Significance of two distinct types of tryptophan synthase beta chain in Bacteria , Archaea and higher plants. Genome Biol. 3 : 0004.1-0004.13.Xie G, Forst C, Bonner C, Jensen RA, et al. (2002) Significance of two distinct types of tryptophan synthase beta chain in bacteria, archaea and ...
It has two beta subunits coding for two different genes, beta 1 and beta 2 subunits are coded by PF1592 and PF1706. This is probably due to gene duplication .The length of beta 1 and 2 subunit is 446, 388 amino acids. Present study deals with the tryptophan synthase beta chain amino ...
Prediction of secondary structure by evolutionary comparison: application to the alpha subunit of tryptophan synthase. Proteins 1987;2:118-129.I. P. Crawford, T. Niermann, and K. Kirschner, Predictions of secondary struc- ture by evolutionary comparison: application to the alpha-subunit of ...
Figure 3. A: Monoisotopic peptide mass spectrum used to identify U1-D as chlamydia tryptophan synthase β chain (TrpB): Nine masses indicated 1-9 matched the TrpB sequence. Trypsin (T) fragments resulting from autodigestion were used to calibrate the spectrum prior to peptide mass mapping with...
et al. Role of IFN-gamma-induced indoleamine 2,3 dioxygenase and inducible nitric oxide synthase in the replication of human cytomegalovirus in retinal pigment epithelial cells. J. Immunol. 162, 957–964 (1999). CAS PubMed Google Scholar Obojes, K., Andres, O., Kim, K. S., Daubener...
Tryptophan synthase (TS) from Salmonella typhimurium is a multi-enzyme complex that produces the essential amino acid tryptophan using a sophisticated allosteric mechanism (Barends, Dunn, & Schlichting, 2008; Miles, 1995; Raboni, Bettati, & Mozzarelli, 2009). TS consists of two subunits, TrpA ...
Target protein abundance was measured by PRM throughout the experiment (Additional file6). Tryptophan biosynthesis pathway protein levels, PHOSPHORIBOSYLANTHRANILATE TRANSFERASE 1 (PAT1), INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE (IGPS), TRYPTOPHAN SYNTHASE ALPHA CHAIN (TSA1), and TRYPTOPHAN SYNTHASE BETA-SUB...
Tryptophan 7-halogenase catalyzes chlorination of free tryptophan to 7-chlorotryptophan, which is the first step in the antibiotic pyrrolnitrin biosynthesis. Many biologically and pharmaceutically active natural products contain chlorine and thus, an und
WARSencodes the cytoplasmic tryptophanyl-tRNAsynthase(WARS2is the mitochondrial counterpart).WARS, like most of the other tRNA synthase encoding genes, is strongly induced (at least at the mRNA level) during amino acid stress as part of the integrated stress response (ISR) [39•]. The ISR ...
Interestingly, the site specific oxidation of Trp residues to NFK in ATP synthase required binding of iron to a metal binding site in close proximity to the AA residue, probably facilitating Fenton-mediated oxidation reactions [238] and illustrating the crucial role of the environment in the ...