Tryptamine 5-hydroxylase-deficient sekiguchi rice induces synthesis of 5-hydroxytryptophan and N- acetyltryptamine but decreases melatonin biosynthesis during senescence process of detached leaves. J. Pineal Res. 52, 211-216 (2012).Park, S.; Lee, K.; Kim, Y.S.; Back, K. Tryptamine 5-...
A plant-specific biogenic amine, serotonin, was produced by heterologous expression of two key biosynthetic genes, tryptophan decarboxylase (TDC) and tryptamine 5-hydroxylase (T5H), inEscherichia coli. The native T5H, a cytochrome P450 enzyme, was unable to be functionally expressed inE. coli. Th...
A putative metabolite of serotonin, tryptamine-4,5-dione, is an irreversible inhibitor of tryptophan hydroxylase: possible relevance to the serotonergic neurotoxicity of methamphetamine 10.1021/tx010037c 11559032 View in Scopus Google Scholar [9] ...
There are great differences in the density of terminals which incidentally, can be assessed not only histologically but also by measuring, in the particular part of the brain, either the concentration of 5-HT, that of tryptophan hydroxylase, or the uptake of [3H] -5-HT. Most of the ...
(MTL), dopamine, and noradrenaline expression levels were measured using enzyme﹍inked immunosorbent assay(Elisa) and immunofluorescence, and key proteins, such as the transient receptor potential (TRP) ion channels/tryptophan hydroxylase (TPH) and olfactory receptor (OR), were determined using western...
There are great differences in the density of terminals which incidentally, can be assessed not only histologically but also by measuring, in the particular part of the brain, either the concentration of 5-HT, that of tryptophan hydroxylase, or the uptake of [ 3 H] -5-HT. Most of the ...
The inhibition of the tryptophan hydroxylase step reduces the conversion of tryptophan to 5-hydroxytryptophan and to serotonin and increases the rate of conversion of tryptophan to tryptamine. A further increase in the tryptamine concentration can be obtained by blocking the normal oxidative deamination ...
A coordinated regulation of geraniol 10-hydroxylase and tryptophan decarboxylase by inoculum size seems to contribute to the effects observed.doi:10.1016/S0168-9452(98)00188-5Adriana ContinRobert van der HeijdenHens J.G. ten HoopenRobert Verpoorte...