The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrein, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, ...
A "trypsin-like" enzyme has been identified and partially purified from bovine adrenal chromaffin granule extracts. This enzyme has a pH optimum of 5 which is near the chromaffin intragranular pH. The enzyme cleaves the peptide bond on the carboxy side of basic amino acids as shown with proenk...
摘要: Trypsin-like proteinases are serine proteinases that recognized peptide residues with positively charged side chains (arginyl or lysyl residues) and that effect hydrolysis of the polypeptide chain onDOI: 10.1007/978-3-540-38918-7_6945 年份: 2008 ...
专利名称：TRYPSIN-LIKE ENZYME DESC1 AND METHOD FOR USING THE SAME 发明人：YASUI SHUICHI,安井 秀一,EGUCHI HIROSHI,江口 広志 申请号：JP特願2002-74117(P2002-74117)申请日：20020318 公开号：JP特開2003-265183(P2003-265183A)A 公开日：20030924 专利内容由知识产权出版社提供 摘要：Array 申请人：...
The results suggest that arachain is not a "trypsin-like" protease but is a peptide hydrolase.Erma C. CameronMendel MazelisPlant PhysiologyCameron EC, Mazelis M (1971) A nonproteolytic ‘trypsin–like’ enzyme. Plant Physiol 48: 278–281...
Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa. 声明 1. A compound of Formula I: P4-P-M-M4 I or a stereoisomer or pharmaceutically acceptable salt thereof, wherein: P-M is pyrazolyl, which is substituted with 0-...
TRYPSIN-LIKE ENZYME DESC1 AND METHOD FOR USING THE 优质文献 相似文献The retrospective problem in sequential population analysis: An investigation using cod fishery and simulated data The retrospective problem is a systematic inconsistency among a series of estimates of population size, or related assessm...
A trypsin-like proteinase was isolated from Streptomyces rimosus culture filtrates obtained from an oxytetracycline production process. The isolation procedure includes ultrafiltration, chromatography on CM-Sephadex, AH-Sepharose and CM-cellulose and gives a homogeneous protein with 19% yield. The enzyme ...
The present study investigates the catalytic activity of a trypsin-like protease (TLP1) and its production management from probiotic bacterium Lactobacillus plantarum subsp. plantarum PTCC 1896. Different culture media were screened for the production of TLP1 at 37 °C. TLP1 was only produced in ...
Trypsin-like enzymeThrombinmdx miceIn order to examine the possible participation of trypsin-like proteases in the onset and progress of muscular dystrophy, we investigated the expression of the trypsin-like protease in muscular tissues in mdx mice. We found that the mRNAs of several trypsin-like ...