Hc-SPI-I8A was a serine protease inhibitor containing a trypsin inhibitor-like cysteine rich (TIL) domain, while Hc-SPI-I8B was not. Hc-SPI-I8A/B were primarily expressed in the hypodermis, intestines and gonads
1A). Sequence and predicted structural analyses reveal the presence of one trypsin inhibitor-like (TIL) domain containing 10 conserved cysteine residues, which are predicted to form 5 disulfide bonds. The P1 residue, located in the inhibitory reactive site, is a tyrosine (Fig. 1B). Alignment ...
别名:Peptidase inhibitor 15; PI-15; 25 kDa trypsin inhibitor; p25TI; Cysteine-rich secretory protein 8; CRISP-8; SugarCrisp; PI15_HUMAN 抗体来源:Rabbit/Mouse 克隆类型:单抗/多抗 性状:Lyophilized or Liquid(冻干粉或液体) 浓度:1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin...
Molecular docking simulations between the inhibitor NcTI with the bovine trypsin (PDB:1S0Q). (A) Amino acid sequence alignment of NcTI with representative members of the MIT-like atracotoxin family. The residues in blue and the squares indicate the residues that are the possible candidates for ...
at theN-terminus and an additional T at position 173 of A0A1D5UB33) listed as “AAI domain-containing protein” since July 2019. Probably, this protein would have not been considered in untargeted LC–MS/MS searches due to its special name without the keywords “amylase” and “inhibitor”...
Cysteine-rich peptideHelicoverpa armigeramRNA expressionSerine protease inhibitorsTrypsin inhibitor-like cysteine-rich domain (TIL)-type protease inhibitors have been reported to inhibit proteases such as trypsin, cathepsin, elastase, and chymotrypsin, and thus play a critical rolein several physiological ...
In this work, a cDNA encoding a novel trypsin inhibitor-like (TIL) cysteine-rich peptide was identified from the skin cDNA library of L. laevis. The 240-bp coding region encodes an 80-amino acid residue precursor protein containing 10 half-cysteines. By sequence comparison and signal peptide...
Pancreatic secretory trypsin inhibitor acts as an effective inhibitor of cysteine proteinases gingipains from Porphyromonas gingivalis. J Periodontal Res. 2007;43:232-236.Bania J, Kubiak A, Wojtachnio K, Polanowski A. Pancreatic secre- tory trypsin inhibitor acts as an effective inhibitor of ...
Cysteine-rich secretory protein (CRISP) trypsin inhibitor polypeptides and polynucleotidesAn isolated polypeptide selected from the group consisting of: (a) an isolated polypeptide encoded by a polynucleotide comprising the sequence SEQ ID NO:24 set forth in Table I; and (b) an isolated polypeptide...
6 Pig Major Acute Phase Protein (Inter-Alpha-Trypsin Inhibitor Heavy Chain 4) During the acute phase response in pigs, a major acute phase protein (pig MAP) can be detected (Lampreave et al., 1994) and has been identified as porcine inter-alpha-trypsin inhibitor heavy chain 4 ...