Nicotinic acid is a common regulator of heat-sensing TRPV1-4 ion channels. Sci. Rep. 5, 8906 (2015).Ma L, Lee BH, Clifton H, Schaefer S and Zheng J: Nicotinic acid is a common regulator of heat-sensing TRPV1-4
内容提示: 分类号: R655.3 学校代码:10392 学科专业代码:100210 学 号:1111003013 福福建医科大学博博士研究生毕业论文 1 TRPV1 和和 4 TRPV4 通道对小鼠肺血管张力的调节作用 Regulation of TRPV1 and TRPV4 Channels in Mouse Lung Vasculature 学学位类型: 科学学位(科研型) 所所在学院: 第一临床 医 ...
这可能是由于大鼠和小鼠在信息诱导的机械性痛觉敏感中的信号转导及TRPV1的作用方式存在物种间差异,或者可能是由于影响一般基因敲除(即TRPV1基因)和特异性药物阻断(TRPV1离子通道蛋白,很可能参与多蛋白信号复合体)中信号的不同机制所致...
关键词:心肌保护;TRPV1;TRPV4;降钙素基因相关肽;P物质;花生四烯酸脂氧合酶 中图分类号:R541.4 文献标识码:A 文章编号:2095-5375(2016)01-0037-004 doi:10.13506/j.cnki.jpr.2016.01.011 ResearchprogressofTRPV1andTRPV4channelsinischemia/oxygenconditioning-inducedcardioprotection ...
Accordingly, TRPV2 is insensitive to intracellular ATP, while, as previously observed with TRPV1, a sensitizing effect of ATP on TRPV4 required an intact binding site. In contrast, ATP reduced TRPV3 sensitivity and potentiation by repeated agonist stimulations. Thus, ATP and calmodulin, acting ...
机译:小鼠膀胱中瞬时受体电位通道TRPV4和TRPV1的差异化定位。 7. Poster session 2Morphogenetic mechanisms290MiR-133 regulates retinoic acid pathway during early cardiac chamber specification291Bmp2 regulates atrial differentiation through miR-130 during early heart looping formationDevelopmental genetics294Associa...
近日,来自美国哈佛医学院的Isaac M. Chiu团队于Science上在线发表题为A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut的文章,利用交叉的化学遗传学方法来确定不同的神经元是如何调节肠...
Although pain is a major human affliction, our understanding of pain mechanisms is limited. TRPV1 (transient receptor potential vanilloid subtype 1) and TRPV4 are two crucial receptors involved in in...
Recent pre‐clinical data indicate that activators of transient receptor potential channels of the vanilloid receptor subtype 1 (TRPV1) may improve the outcome of ischemic acute kidney injury (AKI). The underlying mechanisms are unclear, but may involve TRPV1 channels in dorsal root ganglion neuron...
TRPV1激动剂(Capsaicin)(404-86-4)(98.39%) 英文名称: Capsaicin 国产/进口: 国产 产地/品牌: 百奥莱博 型号: 404-86-4 参考报价: 销售商: 北京百奥莱博科技有限公司 总点击数: 417 更新日期: 2024-11-04 产品类别: 细胞生物学试剂 性能参数 特别提示:包括TRPV1激动剂(Capsaicin)在内,...