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This work was supported by grants from Science and Technology Development Fund of Macau SAR [127/2014/A3], Research Committee of University of Macau [MYRG124-ICMS12-HPM], and National Natural Science Foundation of China [NSFC-81403139-H2809]. Author Contributions Y.W.K., S.M.Y.L. and ...
(31328012); grant from the Natural Science Foundation of Jiangsu Province (BK20130953); from the administration of the traditional Chinese Medicine of Jiangsu Province (Lz13020); from Natural Science Foundation of Guangxi Province (2015GXNSFBA139138); From the Science and Technology Development ...
肺疾病发病机制中的作用 王沐昀 张妍蓓 李锋 ʌ摘要ɔ 作为一种常见的慢性气道炎症疾病,慢性阻塞性肺疾病(C O P D )的发生发展与多种致病因素如香烟烟雾暴露和空气污染相关,现有的抗炎药物对于C O P D 的炎症控制缺乏疗效㊂因此,迫切需要对C O P D 炎症的相关机制进行深入研究㊂瞬时受体电位(T R P ...
This research is supported by the Natural Science Foundation of China (Grant No. 82171452, No. 82060588), Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University (Grant NO. ZNLH201909), the Medical Science Advancement Program of Wuhan University (No....
Guangdong Provincial Science and Technology Program (No. 2019B030301009). Shenzhen Key Medical Discipline Construction Fund (No. SZXK060). SZU Top Ranking Project (86000000210). The authors would like to thank Dr. Jessica Tamanini for editing the manuscript prior to submission. They also thank ...
[NSFC Grant Nos. 31902231 and 31402055], the College Students' Innovation and Entrepreneurship Training Program of Yangtze University [Grant No. 2019110], the Science and Technology Research Project of Department of Education of Hubei Province [Grant No. Q20171305], the Yangtze Youth Talents Fund ...
This work was supported by FWF (Austrian Science Fund) Projects P19820 (to K. G.), P18475 (to M. P.), and P18169 (to C. R.). 2 The abbreviations used are: siRNA small interfering RNA EGF epidermal growth factor PBS phosphate-buffered saline GFP green fluorescent protein FRET fluoresc...
TRPV6 is a calcium-selective ion channel implicated in epithelial Ca2+ uptake. TRPV6 inhibitors are needed for the treatment of a broad range of diseases associated with disturbed calcium homeostasis, including cancers. Here we combine cryo-EM, calcium i
Temperature-sensitive TRP channels are important for responses to pain and inflammation, to both of which tissue acidosis is a major contributing factor. However, except for TRPV1, acid-sensing by other ThermoTRP channels remains mysterious. We show here