To characterize the impact of OxPAPC on different TRP channel family members, we performed calcium imaging-based screening of recombinant TRP channels expressed in HEK-293 cells in a fluorescence imaging plate reader assay (Fig.3a–f). Characteristic agonists for each TRP channel served as a ref...
CROSS-REFERENCE TO RELATED APPLICATIONS Not applicable. STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. BACKGROUND OF THE INVENTION 1. Field of the Invention This invention generally relates to chemicals that bind to receptors in the TRP (transient receptor potential) ion ...