英文: The amounts of iso-tRNAAla changed, tRNA Ala increasing 0% and tRNA Ala decreasing %. There were no remarkable changes in the amounts of iso-tRNAGly.中文: tRNA~(Ala)同功受体的相对含量有变化,其中tRNA_ ~(Ala)增加0%,tRNA_~(Ala)下降%,tRNA~(Gly)同功受体的相对含量无明显变化。
Here, we report that inositol-requiring enzyme 1α (IRE1α) cleaves the anticodon stem-loop region of tRNAGly(GCC) to produce 5′-tRHs (5′-tRH-GlyGCC) with highly selective target discrimination upon endoplasmic reticulum (ER) stress. Levels of 5′-tRH-GlyGCC positively affect cancer ...
Plant mitochondrial genomes lack a number of tRNA genes and the corresponding tRNAs, which are nuclear-encoded, are imported from the cytosol. We show that specific import of tRNAGly isoacceptors occurs in tobacco mitochondria: tRNAGly(UCC) and tRNAGly(CCC) are cytosolic and mitochondrial, while...
The direct regulatory relationship between tiRNAs and splicing-related proteins remain elusive.Papillary thyroid carcinoma (PTC) associated tRNA fragments were screened by tRNA fragments deep sequencing and validated by qRT-PCR and Northern Blot in PTC tissues. The biological function of tRNA fragments ...
甘氨酰-tRNA合成酶的结构,功能和致病机制研究进展 研究已表明,甘氨酰-tRNA合成酶(glycyl-tRNA synthetase,GlyRS)是20种氨酰-tRNA合成酶之一[1].GlyRS是生物体中甘氨酸参与蛋白合成必不可少的催化酶,在甘氨酸参与合成蛋白质过程中,tRNAGly氨酰化是关键环节[2].GlyRS的氨酰化活性功能受到抑制或损害时,蛋白质.....
细胞内有些tRNA分子的反密码子中含有稀有碱基次黄嘌呤(I),含有I的反密码子在与mRNA中的密码子互补配对时,存在如图所示的配对方式(Gly表示甘氨酸)。下列说法错误的
mRNA分子由一条链组成,tRNA分子由两条链组成 相关知识点: 试题来源: 解析 解:A、mRNA分子上的密码子决定蛋白质的氨基酸序列,A错误;B、转录与翻译都遵循碱基互补配对原则,但是配对方式不完全相同,转录时有T与A配对,翻译时没有,B错误;C、由图可知,甘氨酸对应着3种tRNA,l种氨基酸可以由1种或多种tRNA转运,C...
coli can be grouped into three subspecies which are separated by chromatography on benzoylated DEAE cellulose (BDC): tRNA Gly 1 (GGG), tRNA Gly 2 (GGA/G) and tRNA Gly 3 (GGU/C) 1,2 . The tRNA Gly 1 a... C Squires,J Carbon - 《Nat New Biol》 被引量: 119发表: 1971年...
tRNA衍生的小RNA (tDRs)广泛分布于血液和尿液等人体组织中,在癌症的进展中发挥着重要作用。然而,tDRs在结直肠癌(CRC)血浆中的表达及其潜在的诊断价值尚未得到系统的探讨。目前有作者发现血浆中5'-tRF-GlyGCC的表达水平是一种很有前景的CRC诊断生物标志物,该研究于2021年2月发布在《Genome Medicine》,IF:10.675。
A cloned 2.1 kb fragment of rat DNA hybridized to purified tRNAAsp has been sequenced. The result revealed that in addition to the putative gene for tRNAAspGAU(C), the fragment contained the tRNAGlyGGA(G) and tRNAGluGAG genes. The genes for tRNAAsp, tRNAGly and tRNAGlu have the same ...