ROS1 or TRKC solvent-front substitution-mediated resistance.Significance:Repotrectinib (TPX-0005), a next-generation ROS1, pan-TRK, and ALK TKI, overcomes resistance due to acquired solvent-front mutations involvingROS1, NTRK1-3, andALKRepotrectinib may represent an effective therapeutic option ...
答案为使肉制品保持鲜艳的红色,可以在加工过程中添加硝酸盐或者亚硝酸盐。硝酸盐在细菌的作用下(亚硝酸菌),被还原为亚硝酸盐。又由于屠宰后的肉中含有乳酸,在这样的酸性条件下,亚硝酸盐转化为亚硝酸。其反应为: 亚硝酸很不稳定,即使在常温下也要分解产生亚硝基(NO) 此时生成的亚硝基会很快与肌...