Trisomy 13, sometimes called Patau syndrome, is a rare genetic condition that happens when babies have an extra 13th chromosome. Chromosomes in our cells carry DNA, which controls how our bodies develop.Usually, people have 23 pairs of chromosomes, half from each parent. ...
The most common aneuploidy-associated syndromes are: Down syndrome caused by trisomy 21 (T21), Patau syndrome, caused by trisomy 13 (T13), and Edwards syndrome, caused by trisomy 18 (T18) (4). Nuchal translucency (NT) thickness is an established method for the prediction of all three disea...
Background:Partial trisomy of the long arm of chromosome 11 is a rare cytogenetic abnormality. It has been characterized by variable sized duplications that lead to a range of phenotypes including growth retardation, developmental delay/intellectual disability, and distinctive craniofacial abnormalities. ...
The expression of the ETS-2 proto-oncogene, located on chromosome 21, in normal fetal tissues and in neural tissue of a fetus affected by Down syndrome has been investigated. The results show that the ETS-2 proto-oncogene is expressed in almost all the tissues examined and that it is ...