Bienvenido al App de Triple-S Vida para agentes. Esta aplicación te permitirá cotizar, completar y someter solicitudes de seguro de forma electrónica e inmedia…
the amount released in time t, the duration of the drug release, the release rate constant, and the release exponent. The above equation can also be expressed in terms of concentration, with Ctbeing the active agent's concentration at time t and C∞denoted as shown below....
Normalized scRNA expression values from glioblastoma samples, published by Richards et al., were downloaded from the Broad’s Single Cell Portal (https://singlecell.broadinstitute.org/single_cell/study/SCP503). Using the expression data from the primary tumour samples (malignant cells only), cells...
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2(5):401–4. Article PubMed Google Scholar Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, et al. Integrative analysis of complex cancer genomics and ...
Ding, T.T. Fu, S.Y. Peng, S.Y. Chen, J.J. Luo, W.P. Wang Portal hypertension in hepatitis B-related cirrhosis: diagnostic accuracy of liver and spleen stiffness by 2-D shear-wave elastography Hepatol. Res. : the official journal of the Japan Society of Hepatology, 49 (2019), ...
The mRNA expression levels (RSEM expected count, DESeq2 standardized) were obtained from The Cancer Genome Atlas (TCGA), the Genotype-Tissue Expression (GTEx) database, and tumor alterations relevant for genomics-driven therapy (TARGET) data retrieved from the Xena portal site (http://xena.ucsc...
TNBC cells [37]. We therefore asked if PDGFRβ acts as a resistance mechanism upon JAK2 inhibition in our settings. To test this, we exposed both SUM159PT and MDA-MB-231 cell lines to different doses of JAK2 inhibitor, AZD1480 and found an increase in PDGFRβ protein levels along with...
which may form the backbone of future combination therapies. Recent advances in our understanding of TNBC heterogeneity, mutations, and surrogate markers of response such as pCR have enabled the development of multiple treatment options in the (neo)adjuvant setting in order to de-escalate treatment....
Quantitative real-time polymerase chain reaction was performed using SYBR Green PCR Master Mix (Applied Biosystems, cat. 4309155) and designed forward and reverse primers, and the temperature and time conditions of the reaction were as follows: 95 °C for 10 min to activate the agent; 40 conti...
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012;2(5):401–4. https://doi.org/10.1158/2159-8290.CD-12-0095. Article PubMed Google Scholar Gao J, Aksoy BA, Dogrusoz U, et al. Integrative analysis of complex cancer...