Triple-negative breast cancer (TNBC) is a biologically and clinically heterogeneous disease, which has long been considered to present a major unmet need due to its aggressive behaviour and poor prognosis, with
Triple-negative breast cancer (TNBC) is a subtype of breast cancer in which the estrogen receptor and progesterone receptor are not expressed, and human epidermal growth factor鈥搑eceptor 2 is not amplified or overexpressed. Data derived from highly complex molecular technologies, such as microarrays...
Petrosyan, V., Dobrolecki, L.E., LaPlante, E.L.et al.Immunologically “cold” triple negative breast cancers engraft at a higher rate in patient derived xenografts.npj Breast Cancer8, 104 (2022). https://doi.org/10.1038/s41523-022-00476-0 ...
News January 21, 2025 2 min read Save Trial of vaccine for triple-negative breast cancer yields ‘encouraging’ results Nearly 75% of women treated with a novel vaccine designed to prevent triple-negative breast cancer achieved an immune response, according to updated results of a phase 1 trial...
Breast cancer is the most frequently diagnosed cancer globally and the leading cause of cancer-related deaths among women.1 Approximately 15% of breast cancers are classified as triple-negative breast cancer (TNBC). TNBC is characterized by the absence of the estrogen receptor, the progesterone ...
The cancer grows beyond the lymph nodes. Your sentinel lymph node biopsy shows that you have cancer cells after you had chemotherapy to shrink the tumor before surgery. Surgery Surgery can be one of two types. Many doctors think that because triple-negative breast cancer is aggressive, it’s ...
A new study reveals that lacidipine, a common antihypertensive medication, slows tumor growth in triple-negative breast cancer.
Despite significant advances in care, breast cancer remains a leading cause of cancer death among women around the world. Although it occurs less frequently than other subtypes of breast cancer, triple-negative breast cancer (TNBC) is more commonly diagnosed in younger women and associated with ...
Triple negative breast canceris a very aggressive breast cancer subtype which has not been characterized well enough and for this reason it is often fatal. MicroRNAs have the potential to act as therapeutic targets and thus, it is essential that further research is conducted to shed light on the...
Prognostic value of stromal tumor-infiltrating lymphocytes in young, node-negative, triple-negative breast cancer patients who did not receive (neo)adjuvant systemic therapy. J Clin Oncol. 2022;40(21):2361-2374. doi:10.1200/JCO.21.01536PubMedGoogle ScholarCrossref 9. Salgado R, Denkert...