This suggests the possible building of a DNA triple helix between the G-rich neo-synthesized DR1 and the base-paired homologous G.C-rich DR2. In vitro experiments with the purified human DNA polymerase 纬 subunits enabled us to show that the third DNA strand may be used as a primer for...
The Mouse as an Animal Model for Human Diseases Formation of triple helix with DNA or RNA Pyrimidine rich in DNA or RNA can form a triple helix with purine rich sequences in a precise orientation. A number of studies have shown that oligonucleotides can enter cells and form a triple helix...
Triple Helix Strategies and Progress Abstract The binding of single-stranded nucleic acids to a DNA duplex is a phenomenon which has been known for at least 40 years. Recently, it has been recognized that the formation of such triple helices could serve as the basis for the design of site s...
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simulation models, RNA, DNA, DNA conformation, computer simulation, molecular conformation, cordycepinA three-dimensional model of DNA/RNA triple helix that contains a poly(L-deoxyadenosine) (L-dA) chain is proposed based on computer-assisted model building and energy calculations. The model building...
DNA Triple Helix as a Tool to Regulate Cytokine Gene ExpressionThe recognition of promoter DNA by proteins plays a central role in the regulation of gene expression ( 1 ). Methods or agents that can selectively alter the interaction of a protein at a certain site on DNA could potentially ...
(1997) Towards a general triple helix mediated DNA recognition scheme. Chem. Soc. Rev. 26, 63±71.Doronina,S.O. and Behr,J.P. (1997) Towards a general triple helix mediated DNA recognition scheme. Chem. Soc. Rev., 26, 63-71.
【答案】:脱氧寡核苷酸能与双链DNA特异序列结合,形成三链DNA来阻止基因转录或复制,这种脱氧寡核苷酸称为TFO。
重组人CTHRC1蛋白 Recombinant Human CTHRC1/Collagen triple helix repeat-containing protein 1 ,亿迅生物提供各种重组蛋白,重组蛋白产生是应用了重组DNA或重组RNA技术从而获得蛋白质。 详细内容 详细内容 公司简介 本产品仅供科研实验,不得用于医疗或食用。本公司今日报道: ...
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