At each timepoint (d13; 2 days after treatment and d20; 2 days after treatment), primary tumors (n = 9 for each group treated with 1 x PBS, IC/(Fc)/CD20-NKCE-1 or NKp46/(Fc)/CD20-NKCE-1) were resected, fixed by
More importantly, this study uncovers the biological meaning of the age-related decline of mito- chondrial stress response from an evolutionary point of view. Several hypotheses have been proposed to explain why biological aging occurs. The "antagonistic pleiotropy" (multiple effects of a single ...