The human whipworm, Trichuris trichiura, only affects humans and primates, and has a direct life cycle without intermediate hosts. Infection in humans with closely related species such as Trichuris suis (from pigs) or Trichuris muris (from mice) may occur, but the infection is short lived and...
suis, were enriched for transcripts associated with immunomodulation, porins, secreted trypsin-like proteases, and ion/sugar transporters [52]. The study [52] also revealed an upregulation of glucose and lipid metabolism in this tissue, indicating that initial digestion may occur in the stichosome....
T. suis undergoes substantial developmental changes throughout its direct life cycle29. To understand developmental processes in this parasite, we used RNA-seq to characterize transcription in various stages, sexes or body portions (stichosomal versus all non-stichosomal tissues from male and female...
Aaron Jex and colleagues report whole-genome sequencing of adult male and female whipworm, Trichuris suis, from experimentally infected pigs. They also report stage-, sex- and tissue-specific transcriptomes and provide insights into host-parasite interac
suis) that can be transmitted from animals to man. Dog Whipworm Life Cycle References and Suggested Readings: 1) Helminths. In Bowman DD, Lynn RC, Eberhard ML editors: Parasitology for Veterinarians, USA, 2003, Elsevier Science. 2) Phylum Nemathelminthes. In Hobbs RP, Thompson ARC, ...
suis E/S, and so these cells may also be responsible for at least some of the increased IL-6 post Am80-treatment [46]. In conclusion, we show that delivery of the RAR agonist Am80 during a chronic T. muris infection leads to increased Th2 responses, but these are insufficient to ...