Successful aging is a multidimensional concept of which engagement in meaningful activities, and well-being are primary components [53,54,55]. Thus, successful aging was derived from three measures, specifically the community health activities model program for seniors [56] (CHAMPS) questionnaire, ...
Results Participant Flow and Characteristics Participant flow through enrollment, randomization, follow-up, and analysis phases of the trial is shown in Figure 1. After being screened for eligibility, 49 older adults were randomized to treatment (a 6-week intervention [2 hours per week]), and...
The participants will then stand up from their chair, walk 3 m at their fastest speed, turn around, return to their chair, and sit down. The score is the time taken to complete the test. The TUG has shown excellent test–retest reliability (ICC = 0.89) and concurrent validity (...
Osteoarthritis (OA) has long been considered as a degenerative disease of cartilage tissue resulting from bodily wear and tear. However, there is accumulating evidence that inflammation plays a key role in the pathogenesis of OA. In knee OA, the most com
Adolescence is a critical period for the onset and maintenance of anxiety disorders, which raises the importance of intervening early; one possibility of doing so is via digital interventions. Within that research field, at least two important research p
Excess adiposity at diagnosis and weight gain during chemotherapy is associated with tumour recurrence and chemotherapy toxicity. We assessed the efficacy of intermittent energy restriction (IER) vs continuous energy restriction (CER) for weight control and toxicity reduction during chemotherapy. Methods One...
It is imperative that trial samples represent the population who will use the intervention.1-3 Trials are also the last opportunity prior to formal approval to assess treatment effect modification in a controlled setting. Yet disparities persist in clinical trials, with several segments of the US ...
Table 1. Ratings of clinical trial design evidence in support of disease-modification Empty CellNo SupportMild SupportModerate SupportMarked Support Delayed start design with failure to catch up in delayed start design 10.71 33.33 36.90 19.05 Staggered withdrawal design with failure to fall back to ba...
Data on the association between lung function and some dietary patterns have been published. However, it is not yet well known if whether the Mediterranean Diet (MD) pattern can preserve or improve lung function. Our purpose is to evaluate the effect of
All participants are informed that they have an equal opportunity for allocation to the Xiaoyao-pills group or placebos group before enrollment. Data analysts and outcome assessors do not participate in the blinding. Clinical trial related data, such as drug types and affiliated centers, is passed...