Trial registration Chinese Clinical Trial Registration Center, ChiCTR2200061376 (retrospectively registered). Registered June 22, 2022. http://www.chictr.org.cn/listbycreater.aspx. Manuscript Version: 3.0 Manuscript Date: October 10, 2023.Peer Review reports Background Upper limb motor dysfunction after...
We have carried out the largest randomised trial to date of newly diagnosed myeloma patients, in which lenalidomide has been used as an induction and maintenance treatment option and here report its impact on second primary malignancy (SPM) incidence and
Trial registration The trial was approved by Swissmedic (Registration Number: 10001035, 08/22/2022) and the Ethics Committee of Bern (Registration Number: 2022-D0036, 08/22/2022). The trial was registered at ClinicalTrials.gov NCT05934019 on 07–03-2023. Peer Review reports Administrative inform...
This toolbox [17] is based on MATLAB (MathWorks, MA, USA), statistical parametric mapping (SPM) 12 (Wellcome Trust Centre for Neuroimaging, University College London, UK), and diffeomorphic anatomical registration analysis using exponentiated lie algebra (DARTEL) [18]. Structural processing, ...
the comparison of offline (before extinction learning) and online (during extinction learning) rTMS stimulation protocols over the IL demonstrated that stimulation before extinction learning did not lead to significant improvements in fear extinction compared to online stimulation60. To date, no study has...
Secondary Outcome Mechanical ventilation Days on mechanical ventilation The number of mechanical ventilation days from the date of admission to the ICU and the study. Hours Days Secondary Outcome ICU stay Length of stay in ICU The number of days in the ICU from ICU admission until patient's disc...
(interviews, online surveys). It provides user-level access control as it is only accessible to authorized personnel. To ensure traceability of relevant processing operations, changes with username, date, time, and modification are logged (audit trail) and can be controlled at any time. The ...
Previously, the HADS has been used as primary outcome measure in the largest MBI-RCT in PD to date [13], and RCTs investigating the effects of MBCT in other somatic illnesses have implemented the HADS as primary out- come as well [25, 26]. Good psychometric properties of the Dutch H...
It has been shown that AKBA activates cellular 15-LOX-1 via an allosteric site accomplishing robust SPM formation in M2 macrophages, promoting inflammation resolution [36]. In addition, the inflammation-resolving activities of DHA and EPA have been linked to the generation of SPM [37]. The ...
It has been shown that AKBA activates cellular 15-LOX-1 via an allosteric site accomplishing robust SPM formation in M2 macrophages, promoting inflammation resolution [36]. In addition, the inflammation-resolving activities of DHA and EPA have been linked to the generation of SPM [37]. The ...