Heart failure is a complex syndrome in which the heart is unable to deliver sufficient blood to meet the metabolic needs of organs throughout the body in the presence of normal filling pressures. Despite approval of multiple drugs for treating heart failure patients over the past 50 years, the...
With heart failure, your heart has a hard time pumping blood to the rest of the body. This causes fluid to build up, leading to symptoms like swelling and trouble breathing. Once you get symptoms, heart failure is considered advanced, or stage C. Stage D is the most advanced stage. You...
Compared with heart failure (HF) care 20 to 30 years ago, there has been tremendous advancement in therapy for ambulatory HF with reduced ejection fraction with the use of agents that block maladaptive neurohormonal pathways. However, during the past decade, with few notable exceptions, the frequ...
This innovative model, which mimics the development ofHFpEFin the context of heart failure and diabetes, enabled researchers to explore the cellular and molecular dynamics of heart muscle contraction and relaxation in both male and female mice. Calcium plays a pivotal role in heart muscle contraction...
Heart attack is the death of a segment of heart muscle caused by the loss of blood supply. 心肌梗塞,是由于心肌缺血而导致的心脏肌肉坏死。 The blood supply is usually lost because a coronary artery, one that supplies bloo...
Dave Dixon, PharmD, discussed heart failure treatments in the pipeline and what he sees for the future of pharmacists in cardiovascular care.Pharmacy Times spoke with Dave Dixon, PharmD, an associate professor and department chair at the Virginia Commonwealth University School of Pharmacy.Q:...
Heart failure begins when the heart muscle is weakened or damaged. This may occur for a variety of reasons, including heart attack or a prolonged period of high blood pressure. Sometimes the cause of heart failure is unknown. When the heart muscle begins to fail, the heart does not pump as...
Heart attack is the death of a segment of heart muscle caused by the loss of blood supply. 心肌梗塞,是由于心肌缺血而导致的心脏肌肉坏死。 The blood supply is usually lost because a coronary artery, one that supplies blood to the heart muscle, is blocked by a blood clot (coronary thrombosis...
As a result, <1% of patients with heart failure are receiving all life-prolonging treatments at trial-proven doses. A major impediment to the widespread adoption of trial-based treatments is a lack of any existing framework that would allow physicians to describe the adequacy of care. To ...
Heart attack is the death of a segment of heart muscle caused by the loss of blood supply. 心肌梗塞,是由于心肌缺血而导致的心脏肌肉坏死。 The blood supply is usually lost because a coronary artery, one that supplies blood to the heart muscle, is blocked by a blood clot (coronary thrombosis...