Metastatic breast cancerNanoparticlesTargeted therapyDespite advances in breast cancer treatments and related 5-year survival outcomes, metastatic breast cancer cures remain elusive. The current standard of care includes a combination of surgery, radiation therapy and drug therapy. However, even the most ...
Two innovative treatments for metastatic breast cancer are in development. Dr. Linda Vahdat is testing a drug that reduces the body's level of copper, an element that cancer tumors need to spread. But more research and treatments are needed. Dr. Jon
Drugs used after and in addition to surgery are calledadjuvant therapy(辅助治疗). Chemotherapy or other types of therapy prior to surgery are calledneoadjuvant therapy(新辅助治疗). There are currently three main groups of medica...
Komal Jhaveri, MD, FACP, a medical oncologist at Memorial Sloan Kettering Cancer Center, discusses sequencing treatments for patients with metastatic HER2-positive breast cancer. When a patient begins frontline treatment, Jhaveri recommends the use of trastuzumab (Herceptin), pertuzumab (Perjeta), and ...
Dr Rozenblit on Pembrolizumab Outcomes by TMB Status in HR+ Metastatic Breast Cancer Dr Lloyd on the Effects of ESR1 Mutations on Elacestrant Outcomes in HR+ Advanced Breast Cancer Unveiling the Latest in HER2+ Breast Cancer and Beyond With Drs Sara Hurvitz and Neil Iyengar ...
can spread from yourbreastto other parts of your body, most often to your bones,lungs,liver, orbrain. This is calledadvanced breast cancer. You may also hear it called metastatic or stage IV disease. Although it’s in other areas, it's still breast cancer and doctors treat it with breas...
When you find out you haveadvanced breast cancer, called metastatic or stage IVcancer, you probably have a lot of questions. That's understandable. "The goals of therapy are to prolong life while at the same time maintaining a good quality of life," says Julie Gralow, MD, of the Seattle...
In addition, a drug called dexrazoxane that could reduce cell damage has recently been approved for patients with metastatic breast cancer who receive high doses of doxorubicin. Other treatments, such as radiation, can affect the heart arteries and cause the development of coronary artery disease or...
SUMMARY HER2 positivity defines a molecular subtype of breast cancer with aggressive biological behavior. HER2 has been clinically validated as a prominent therapeutic target in breast cancer, and an abundance of data from clinical trials proving the efficacy of trastuzumab, a humanized anti-HER2 monocl...
Twenty-one premenopausal patients with metastatic breast cancer (unselected for receptor status) were treated during 3–14 months with the potent LHRH-agonist Buserelin (Hoe 766) as a first-line therapy. In one-third of 12 patients treated with Buserelin alone an objective tumour response was obse...