Two new clinical trials to test potential treatments forlong COVIDare now set to launch, the National Institutes of Health said Monday, opening enrollment for the first of an array of federally-funded studies aimed at evaluating treatments for long-term symptoms still faced by many COVID-19 sur...
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Long COVIDSARS-CoV-2COVID-19RehabilitationRandomised controlled trialCoronavirus disease-19 (COVID-19) infection causes persistent health problems such as breathlessness, chest pain and fatigue, and therapies for the prevention and early treatment of post-COVID-19 syndromes are needed. Accordingly, ...
Long Covid has baffled doctors throughout the pandemic, but some are seeing patient symptoms alleviated with low-dose naltrexone.
This study is registered with ClinicalTrials.gov, NCT05620160. Findings Between Nov 12 and Dec 30, 2022 when the zero COVID policy was abolished nationwide, a total of 1359 patients underwent randomization, 680 were assigned to leritrelvir group and 679 to placebo group. The median time to ...
Since high mortality rates from sepsis induced DIC due to COVID-19 infection has also been associated with thrombotic events and elevated levels of D-dimer, randomized controlled trials of using anticoagulant therapy with heparin is urgently required. This is especially important in patients on ...
But a couple of protease inhibitor cocktails have already struck out; Remdesivir, a Gilead Pharmaceuticals drug originally targeted for Ebola, looks more promising; it has been repurposed and is undergoing extensive clinical trials for COVID-19. One of the most ex...
51 RT-PCR positive COVID-19 patients were recruited between November 2020 and July 2021. 34 patients were allotted to receive 0.5 Gy single session LDRT along with standard pharmacologic therapy while 17 patients received standard pharmacologic therapy alone. All had SpO2 <94% on room air, respi...
Randomized controlled trials Viral infection This article is cited by Clinical course and management of COVID-19 in the era of widespread population immunity Eric A. Meyerowitz Jake Scott Muge Cevik Nature Reviews Microbiology(2024) Omicron Spike confers enhanced infectivity and interferon resistance to...
Most importantly, both the trials recruited general, but not severe, COVID-19 patients for study [19, 33]. According to our analysis, however, the association of tocilizumab with clinical benefits is even stronger among severe COVID-19 patients. The most recently published prospective randomized ...