or urine albumin to creatinine ratio > 300 mg/g [61]. The effect of CKD on mortality appears to be less pronounced in HFpEF than in HFrEF [59]. CKD itself has been associated with a higher incidence of HFpEF, as renal dysfunction can contribute to fluid overload and increased cardia...
As to kidney function, there is an increasing risk of nephropathy in the course of interstitial nephritis after 10–15 years of lithium administration, reflected by a higher creatinine concentration and lower glomerular filtration rate (GFR). The risk factors for such renal impairment include high ...
Current biomarkers are not efficient at detecting Pb-induced nephrotoxicity. In occupational Pb exposure, serum creatinine and blood urea nitrogen (BUN) are not suitable for evaluating renal dysfunction11,12. Our previous study demonstrated that rats with low-level Pb-induced nephrotoxicity had higher ...
(TEAE). Most TEAEs were mild to moderate. There was no Serious Adverse Event. Diarrhea, transiently elevated creatinine and adaptive headache were frequently reported adverse drug reaction. We conclude that ZSP1601 is well-tolerated and safe, showing effective improvement in liver chemistries, liver ...
groups: a higher percentage of black people than white people presented with elevated levels of creatinine, AST, or inflammatory markers; while white people showed lower white-cell, lymphocyte, or platelet counts, more elevated levels of brain-type natriuretic peptide, lower sodium levels [104]. ...
Patients who did not tolerate the run-in phase had lower systolic blood pressure, higher serum creatinine levels, and had a history of being more intolerant of an angiotensin-converting enzyme inhibitor, angiotensin receptor blocker, or β-blocker therapy. A total of 167 patients were randomly ...
Stage 1 is defined by an increase in serum creatinine level by 0.3 mg/dL or greater within 48 hours or an increase in serum creatinine level to 1.5 times or greater than baseline, which is known or presumed to have occurred within the prior 7 days, or a urine output of less than 0.5...
Acute kidney injury, either an increase in serum creatinine ≥ 0.3 mg/dL or a 50% increase in serum creatinine from baseline, is associated with ketorolac use in children with SCD hospitalized for pain [76]. Increasing intravenous fluids to maintain urine output > 0.5 to 1 mL/kg/...
Partial splenic embolization (PSE) is a non-surgical procedure which was initially used to treat hypersplenism. Furthermore, partial splenic embolization can be used for the treatment of different conditions, including gastroesophageal variceal hemorrhag
[2]. Tau is a microtubule-associated protein that contributes to the stability of the cytoskeleton and is found predominantly in axons [1,9]. It is the most abundant microtubule-associated protein in the brain, and its dysfunction can be detrimental [2]. As new tauopathies continue to be ...