A clinical trial using Fluosol in the management of sickle cell crisis was undertaken in seven patients, three men and four women, aged 18-37 y, with homozygous S-S disease. Patients were randomized within 12 h of hospital admission to standard supportive care, with or without Fluosol, 20 ...
Sickle cell disease or sickle cell anemia is the most common of the hereditary blood disorders among black people of African descent worldwide. Learn about symptoms, treatment, causes, inheritance, testing, complications, and more.
Sometimes a red blood cell exchange is performed. This process removes some of the sickle blood cells and replaces them with normal (non-sickle) blood cells. It is done when the sickle cell crisis is so severe that other forms of treatment are not helping. Pain crises Pain crises in ...
First evidence of subclinical renal tubular injury during sickle-cell crisis. Orphanet J Rare Dis. 2014;9:67. Article PubMed PubMed Central Google Scholar Baddam S, Aban I, Hilliard L, Howard T, Askenazi D, Lebensburger JD. Acute kidney injury during a pediatric sickle cell vaso-...
Norton Children’s Sickle Cell Disease Program The Adult Comprehensive Sickle Cell Program at Norton Cancer Institute works in tandem with Norton Children’s Hospital to prevent a sickle cell crisis in a patient, care for a crisis if it occurs and manage long-term effects of the disease. Gene...
In the Phase 3 clinical trial, researchers at 20 to 25 sites around the country will be seeking up to 225 research volunteers, age 5 years and older, with a diagnosis of sickle cell anemia or sickle beta O-thalassemia who have a history of at least two episodes of painful crisis during...
A phase I trial of the anti‐sickling agent AES‐103 was also discontinued after 3 months due to unexplained aplastic crisis. Empiric trials of oral magnesium and omega‐3 fatty acids provided no measurable clinical benefit. In February 2014, she was admitted for acute painful crisis that ...
A therapeutic plan that emphasized oral narcotic analgesia was instituted for the treatment of painful crisis of sickle cell anemia. Of the 100 adult sickle cell syndrome patients registered at North Central Bronx Hospital, 15 were identified as using the emergency department facilities three or more...
Aplastic crisis in patients with sickle cell disease who develop a parvovirus infection may be associated with extensive bone marrow necrosis as well as ac... ME Conrad,H Studdard,LJ Anderson - 《American Journal of the Medical Sciences》 被引量: 72发表: 1988年 Intravenous urea in treatment of...
Enhanced Levels of Soluble VCAM-1 in Sickle Cell Patients and Their Specific Increment during Vasoocclusive Crisis Adhesion of sickle erythrocytes to vascular endothelium plays a central role in sickle cell disease complications. Cytokines and adhesion molecules are cri... A.J. Duits and R.C. Piet...