Crawford MH, Karliner JS, O'Rourke RA, et al: Pro- longed Q-T interval syndrome: Successful treatment with combined ventricular pacing and propranolol. Chest 1975:68:369-371.Crawford MH, Karliner JS, O'Rourke RA, Friedman WF. Prolonged QT interval syndrome: successful treatment with ...
a prolonged QT interval (corrected for heart rate) carries a twofold increase in the risk of coronary events and cardiovascular death, after adjusting for the effects of age, sex, diabetes mellitus, serum cholesterol level, serum creatinine level, smoking, left ventricular hypertrophy (LVH) and 24...
Usually, the QT interval lasts about a third of each heartbeat cycle. But with long QT syndrome, this ratio is different. Your doctor might do genetic tests or check whether certain medicines trigger LQTS. They might also do tests to see if you have electrolyte imbalances in magnesium, ...
In people with long QT syndrome, the interval lasts longer than it should because heart muscle cells are having trouble getting ready for the next contraction.A prolonged QT interval does not cause symptoms. However, the delay in recharging upsets the electrical timing of the heart. This makes ...
Prolonged QT interval QT interval longer than 500 msec (on at least 2 separate ECGs): Withhold until QTc interval is below 481 msec or recovery to baseline if baseline QTc 481 or longer msec, then resume with a 150-mg dose reduction ...
Prolonged QT interval in Rett syndrome. Arch Dis Child. 1999;80(5):470–2. CAS PubMed Central Google Scholar McCauley MD, Wang T, Mike E, et al. Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Sci Transl Med. 2011;3(113):...
A prolonged QT interval can result from congenital abnormalities in cardiac repolarization, although it is more commonly seen as a consequence of hypokalemia or the use of Type IA antiarrhythmics such as quinidine or TCAs. Women are more susceptible than men to this arrhythmia.21 This arrhythmia ...
In addition, the list of possible interactions is long including frequently used medications as atorvastatin (increased risk of myopathy and rhabdomyolysis), dom- peridone (risk of prolonged QT interval), clopidogrel (decreased antiplatelet effect), fluconazole (increased verapamil exposure) and lithium ...
[49], another receptor tyrosine kinase that regulates myeloblast development [50]. Quizartinib has been shown to be an inhibitor of potassium channels (IKs), the slowly activating component of delayed rectifier potassium current, and is associated with prolongation of the corrected QT interval (QTc...
- A 37-day old term infant, treated with cisapride (1.2 mg/kg/d) and ranitidine for regurgitations, was hospitalized for malaise. A prolonged QT interval (with isolate ventricular extrasystoles), noted at admission, disappeared rapidly after cisapride withdrawal. Linkage to cisapride was probable...