However, the multitude of treatment options also presents a challenge to select the best options tailored to the specific patient situation. Lenalidomide is increasingly being used as part of frontline therapy i
Ola Landgren, MD, PhD; Sagar Lonial, MD; and Joshua Richter, MD, review current available treatment options and factors to consider when selecting therapy for patients with multiple myeloma who experience a first relapse.
In addition to emerging treatment options, the speakers addressed the importance of individualized decision-making when treating patients with multiple myeloma. Image credit: freshidea | stock.adobe.com During a presentation at the National Comprehensive Cancer Network Annual 2024 Conference in Orlando, ...
Post-ASCT maintenance options for mye- loma patients is summarized in Fig. 2. CONCLUSION Post-ASCT maintenance therapy with lenalido- mide or bortezomib is the standard of care for myeloma patients to prolong PFS and poten- tially OS. The type of maintenance therapy depends on multiple factors...
With the dosing Monoclonal antibodies for multiple myeloma S Lonial et al 529 schedule tested, the most common AEs were anemia, fatigue and nausea; the MTD of MOR202 was not reached in this study. Infusion-related reactions were observed in 31% of patients, yet only in those who received...
Thomas Martin, MD:Let’s talk about relapsed and refractory myeloma. When somebody has evidence of relapse, what do you look at to try to help you decide what treatment to give? Yvonne Efebera, MD:The cytogenetics. I try to do a bone marrow biopsy. How long from the initial transplant...
Relative efficacy of treatment options in transplant-ineligible newly diagnosed multiple myeloma: results from a systematic literature review and network meta-analysisMultiple myelomanetwork meta-analysissystematic literature reviewtreatment-naiveEstablished treatments for transplant-ineligible (TNE) patients with ...
Multiple myeloma All criteria must be met: Hypercalcaemia: serum calcium >11.5 mg/dl or Renal insufficiency: serum creatinine >1.73 µmol/l (or >2 mg/dl) or estimated creatinine clearance <40 ml/min Anaemia: normochromic, normocytic with a haemoglobin value of ≥2 g/dl below the lowe...
Multiple Myeloma (MM), the second most common blood cancer in adults, is a clonal plasma cell malignancy within the bone marrow characterized by osteolytic bone lesions, renal disease, and immunodeficiency. It is now well established that MM cell- induced disruption of the bone marrow homeostasis...
The aim is to assist clinicians and researchers in gaining a deeper understanding of these diverse treatment options, enabling them to carry out effective treatment and advance their research more efficiently.Similar content being viewed by others Molecular targeted therapy for anticancer treatment ...