A recently introduced model solves these technical problems and provides a solid theoretical basis for the study of populations evolving in continuous space. We present a detailed algorithm to simulate...
Mucositis is a significant complication of intensive chemotherapy or hematopoietic cell transplantation (HCT), with few treatment options. Ketamine mouthwashes have been used for pain relief, but supporting evidence is limited. The primary objective of this study was to assess the reduction in pain ...
hair loss, mouth sores, stomach upset: rapidly dividing cells in hair roots and cells that line the digestive tract may also be affected. As a result, side effects may includeloss of hair, poor appetite, nausea and vomiting, diarrhea, or mouth and lip sores (mucositis). ...
I’m really excited about [this therapy] and oral SERDs, mostly because it’s adding treatment options for our hormone receptor–positive patients, and we need more hormone-based therapies. [These agents are] generally easier to tolerate, [patients don’t need] to come in and g...
Jeannie Woith, BSN, RN, LMT, The James Cancer Hospital, The Ohio State University, discusses the treatment of oral mucositis in patients with head and neck cancer.Jeannie Woith, BSN, RN, LMT, The James Cancer Hospital, The Ohio State University, discusses the treatment of ora...
The restoration of barrier function by growth- factor administration has been highly successful in the treatment of inflammatory bowel disease161 and oral mucositis associated with cytotoxic therapy162. Concluding remarks Despite an enormous increase in our understanding of the immune mechanisms involved in...
Given the unsatisfactory treatment options in the second line and above, and the fact that the disease has a median progression-free survival (PFS) rate – meaning the length of time that a patient lives with disease but does not get worse – of less tha...
Also, we look for lesions in the mouth: mucositis-like ulcers, sores. Weight loss is a very important sign when it comes to evaluating chronic GVHD. In 2014, the National Institutes of Health [NIH] standardized the way we do scoring for chronic GVHD.3 What we do now when we evaluate ...
Especially relevant to radiotherapy is the increased risk of mucositis in older patients, particularly evident when treating cancers of the head and neck region [77]. Weight loss also has independent prognostic value in this group of patients [78], therefore ensuring adequate supportive care and ...
and impaired release of toxic payloads into the cytoplasm. Combination therapies are more promising than single-agent therapies for overcoming drug resistance. FDA-approved ADCs provide valuable treatment options for difficult-to-treat patient populations, but drug resistance is a frequently encountered li...