Opinion statement Despite its history as one of the most impactful toxicities associated with cytotoxic cancer therapy, oral mucositis (OM) remains an unmet clinical need which affects hundreds of thousands of patients. Descriptions of its complex pathogenesis have provided mechanistic targets which are ...
Colorectal Cancer Sabine Hofmann1, Janina Vetter1, Christiane Wachter1, Doris Henne-Bruns1, Franz Porzsolt2 and Marko Kornmann1* Abstract Background: A variety of multimodal treatment options are available for colorectal cancer and many patients want to be involved in decisions about their therapies...
Severo MLB, Thieme S, Silveira FM, Tavares RPM, Gonzaga AKG, Zucolotto SM, et al. Comparative study of royal jelly, propolis, and photobiomodulation therapies in 5-fluorouracil-related oral mucositis in rats. Support care cancer Off J Multinatl Assoc Support Care Cancer. 2022;30:2723–34. ...
Treatment for Oral Mucositis-Current Options and an Update of Small Molecules Under Development. January 17, 2021 [MEDLINE Abstract] Molecular-Driven Therapy in Advanced Thyroid Cancer. January 10, 2021 [MEDLINE Abstract] Re-evaluation of Sentinel Lymph Node Biopsy for Melanoma. ...
69 Twelve out of these patients had received prior systemic chemotherapy for MPM. Two objective partial responses were noted and four patients received ≥six cycles of therapy. The treatment regimen was tolerated well. Given the lack of proven options for salvage therapy for MPM, these promising ...
Table 5. Summary table of current options to treat infections due to ESBL-producing Enterobacteriaceae in different groups of patients Group1Characteristics of infection in each groupOptions for treatment (dosing with normal renal function) 1 Severe infections; or Infections with a high-risk source; ...
Surgical options The surgical treatment for sialorrhea is the last-choice therapeutic option and it is suggested: In case of persistent moderate sialorrhea not responding to conservative treatments. In severe sialorrhea cases in whom previous treatment trials have failed or have had limited results with...
and impaired release of toxic payloads into the cytoplasm. Combination therapies are more promising than single-agent therapies for overcoming drug resistance. FDA-approved ADCs provide valuable treatment options for difficult-to-treat patient populations, but drug resistance is a frequently encountered li...
oncology healthcare providers ranked treatment options for their patients. It uses natural language processing and machine learning to aggregate and process patient medical records into a structured format, which feeds into an ensemble of AI models called xCORE that ranks potential treatment options ...
Doctors should be educated about treatment options for chronic pain, including non-pharmacologic therapies, as well as about patient risk assessment and proper prescribing, while patients should be educated about both the benefits of opioid analgesics and their potential risks, including death and side...