COVID-19 has been a major global health concern for the past three years, and currently we are still experiencing coronavirus patients in the following years. The virus, known as SARS-CoV-2, shares a similar genomic identity with previous viruses such as SARS-CoV and MERS-CoV. To combat t...
Clean water is a limited 【2】 in many parts of the world. Drinking dirty water 【3】 several thousand children in developing countries every day.Nearly one-fifth of the would population don’t have 【4】 clean water. The functions of the 【5】 Cases of diarrhea in Pakistan and Kenya ha...
The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group). Conclusions and Relevance In this randomized clinical trial of high-risk patients with mild to moderate COVID-19, ivermectin treatment during early illness did not ...
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to societies and economies. Until now, effective therapeutics against COVID-19 are in high demand. Along with our improved understanding of the structure, function, and pathogenic process of SARS-CoV-2, many sm...
The gastrointestinal adverse effects induced by this antibiotic include abdominal cramping, nausea, vomiting, and diarrhea. Erythromycin is a motilin receptor agonist that binds to gastrointestinal smooth-muscle membrane receptors, displacing the endogenous ligand motilin. Erythromycin therapy did not resolve...
Ensitrelvir (125 mg tablets; dosage and administration, 375 mg on day 1 and 125 mg on days 2–5) has been granted regulatory approval in Japan for COVID-19 treatment (Shionogi & Co. Ltd, 2024). In an interim analysis of the phase 3 SCORPIO-SR trial, ensitrelvir treatment was ...
leads to a range of disease conditions, primarily due to seriously impaired immunity due to the invasion of the virus. AIDS leads to a decrease in the body's self-healing mechanism and many opportunistic infections like Tuberculosis, Pneumonia, fungal infection; diarrhea, etc. affect the body. ...
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease is a virally encoded protein that is essential across a broad spectrum of coronaviruses with no close human analogs. PF-00835231, a 3CL protease inhibitor, has exhibited potent in vitro antiviral activity ag...
As a class, PIs are associated with mild to moderate nausea, diarrhea, and dyslipidemia. However, these adverse effects occur less frequently with newer PIs. All PIs may be associated with cardiac conduction abnormalities, particularly PR prolongation.69...
This systematic review and meta-analysis assesses reports of clinical experiences of patients with COVID-19 and immunosuppression who were treated with