主要疾病: 帕金森病(Parkinson’sdisease,PD) 阿尔茨海默病(Alzheimer’sdisease,AD) 亨廷顿病(Huntingtondisease,HD) 肌萎缩侧索硬化症(amyotrophiclateral sclerosis,ALS) 本组疾病的病因和发病机制尚不清楚, 有关假说: 兴奋毒性(excitotoxicity) 细胞凋亡(apoptosis) 氧化应激(oxidative...
Parkinson disease (PD) is a progressive degenerative neurological disorder characterized by resting tremor, bradykinesia, cogwheel rigidity, and postural instability.1 In the later stages, approximately 25% or more of patients develop cognitive compromise. The cardinal pathological features of PD are ...
Parkinson's Disease and Related Disorders, Part II Susan H.Fox,Anthony E.Lang, inHandbook of Clinical Neurology, 2007 Publisher Summary Treatment ofParkinson's disease(PD) is based on dopamine replacement, either in the form of the dopamine precursor,levodopaor via directly actingdopamine receptor...
Eventually, realizing I could not access those drugs unless I was in a clinical trial, I turned to articles concerning neurodegeneration of all types—dementia, Parkinson’s disease, Huntington’s, and Lou Gehrig’s disease. 56 Knowledge of the subject matter I had only two options: ...
Decision-Making in Adult Neurologydoi:10.1016/B978-0-323-63583-7.00085-0Andres DeikDavid Coughlin
Treatment of parkinson's disease and related disorders Described herein are compositions and methods for the treatment of Parkinson's disease (PD) and/or to protect dopaminergic nigrostriatal neuronal cell bodies from 6-OHDA-induced neurotoxicity in a mammal. In various embodiments of the in... P...
Amphetamines are thought to cause the release of catecholamines from central neurones. Their action in Parkinson's disease may be limited because of pre-... J Parkes,D Tarsy,C Marsden,... 被引量: 0发表: 0年 Drugs, Stem Cell Surgery. What Better Help in the Process of Parkinson's Dis...
Parkinson's disease (PD) is a disease of the central nervous system. It causes problems with body motions, including:Tremor (shakiness) Rigidity (muscle stiffness) Slowed body movements Unstable posture Difficulty walking PD develops when certain nerve cells (neurons) in the brain die. ...
GIUSEPPE BARTHOLINIUS3701829 * Jul 9, 1971 Oct 31, 1972 Hoffmann La Roche Treatment of parkinson's diseaseUS3701829 * 1971年7月9日 1972年10月31日 Hoffmann La Roche Treatment of parkinson's disease
1) Motor symptoms of Parkinson's disease Tremors: Bradykinesia: Rigidity: Postural instability: Loss of facial expression (apathetic expression) Reduced eye blinking Changes in speech Increased salivation Blurred vision Micrography (calligraphy changes and the letters become small) ...