Epilepsy is a chronic disorder of the nervous system caused by abnormal discharges from brain cells. Structural, infectious, metabolic, immunologic, and unknown causes can contribute to the development of seizures. In recent years, there has been increas
infectious, metabolic, immunologic, and unknown causes can contribute to the development of seizures. In recent years, there has been increasing attention on epilepsy caused by genetic metabolic disorders. More than two hundred inherited metabolic disorders have been identified ...
The biguanide metformin is an oral antihyperglycemic drug widely used in the management of non-insulin-dependent diabetes mellitus (NIDDM) which acts by improving hepatic and peripheral tissue sensitivity to insulin. Its major drawback is the possibility of developing lactic metabolic acidosis in patient...
These results indicate that there could be a link between acidosis, TGF-β1 production and GPR65 signaling in both macrophages and HSCs. Hence, the role of HSC-GPR65 signaling in the pathogenesis of fibrosis cannot be completely ruled out since activated HSCs also produce TGF-β1. Perhaps ...
SC Chen - 《Indian Journal of Pediatrics》 被引量: 4发表: 1998年 Spironolactone-furosemide combination therapy and acid-base disorders in liver cirrhosis patients. OBJECTIVE\nRespiratory alkalosis (RA) and dilutional hyperchloremic acidosis (DHA) are the most common acid-base balance (ABB) disorde...
26. Di Iorio BR, Bellasi A, Raphael KL, Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: The UBI Study: J Nephrol, 2019; 32(6); 989-1001 27. Jones EL, Wainwright TW, Foster JD, A systematic review of patient reported outcomes and patie...
To achieve the goal of the World Health Organization to eliminate viral hepatitis as a major public health threat by 2030, the Chinese Society of Infectious Diseases and the Chinese Society of Hepatology convened an expert panel in 2019 to update the gui
Lactic acidosis during Entecavir treatment in decompensated hepatitis B virus-related cir- rhosis. Dig Liver Dis 2011; 43: 1027-8. [CrossRef]Marzano A, Marengo A, Marietti M, et al. Lactic acidosis during entecavir treatment in decompensated hepatitis B virus-related cirrhosis [letter]. Dig ...
symptoms such as fever, drycough, fatigue, anxiety, insomnia,nasal congestion,runny nose, sore throat,myalgiaand diarrhea.4,5,6The severe cases may rapidly developacute respiratory distress syndrome(ARDS), refractorymetabolic acidosis,septic shock,hypoxemiaandmultiple organ dysfunction syndrome(MODS).7,...
Available data from various studies show that NAFLD may be the hepatic manifestation of metabolic syndrome[7]. The spectrum of both diseases ranges from benign steatosis to hepatitis to cirrhosis and hepatocellular carcinoma. Most patients with NAFLD or ALD have hepatic steatosis...