A process is provided for inhibiting symptoms of intestinal dysbiosis in a subject that includes the oral administration to the subject suffering from intestinal dysbiosis an IgA, IgM, or a combination thereof. When administered in a therapeutic quantity based on the subject characteristics and the ...
[Involvement of intestinal dysbiosis in the etiopathogenesis and treatment of autism spectrum disorder: a bibliographic review]. INTRODUCTION\nAutism spectrum disorder is a neurodevelopmental disorder with phenotypic heterogeneity and variable symptomatic course of partly unknown eti... M. Real-López,M. ...
An imbalance of the intestinal bacteria representation (dysbiosis) could lead to different diseases, ranging from obesity and diabetes, to neurological disorders including Alzheimer's disease (AD). The term "gut-brain axis" refers to a crosstalk between the brain and the gut involving multiple ...
The intestinal immune response remains the key focus of developing therapies as well. In the past decade, the concept of dysbiosis of the gut microbiome has emerged as a potential pathogenetic focus in IBD, and with this a burgeoning interest in manipulating the microbiome as a means of ...
We used the M-SHIME(), an in vitro simulator for the human intestinal microbial ecosystem, to study the effect of supplementing a single dose of B. pullicaecorum 25-3(T) on lumen- and mucus-associated microbiota of eight individuals. Butyricicoccus pullicaecorum was more abundant in mucus...
intestinal wall dysfunction due to leakage of the intestinal epithelial barriers [44]. Changes in intestinal composition and components of the mucosal barrier alter the usual equilibrium of the microbiota, both in the abundance and diversity of bacteria, which results in intestinal dysbiosis in which ...
We showed that this combined formulation preserves barrier function, reduces severity of colitis and protects from severe anaphylactic responses to food with a short-term treatment. In our mouse model of peanut allergy, where the mice were previously exposed to vancomycin to induce dysbiosis, we ...
For instance, cirrhosis and depression have been linked to intestinal dysbiosis, which results in intestinal barrier disruption, increasing bacterial translocation. Increased bacterial translocation then activates circulating immune cells, which produce cytokines and induce systemic inflammation.227 In comparison...
Fingolimod has beneficial effects on multiple diseases,including type 1 diabetes(T1D)and numerous preclinical models of colitis.Intestinal dysbiosis and intestinal immune dysfunction contribute to disease pathogenesis of T1D.Thus,the beneficial effect of fingolimod on T1D may occur via the maintenance of...
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