Since 1959 657 girls have been seen because of tall stature. 213 have received estrogen therapy to control growth rate. In December 1975 letters were sen... HN Wettenhall - 《Pediatric Research》 被引量: 1发表: 1969年 Evidence for autosomal recessive inheritance in cerebral gigantism Three case...
Research on the mechanism of action has shown that apoptosis induced by estrogens is regulated via the estrogen receptor and growth factor signalling pathways. High-dose estrogens have a negative safety image, especially in terms of side-effects and increased rates of cardiovascular disease, but the...
Phytoestrogen (PE) is a group of natural non steroid compound which displays estrogen like activity because of their structural similarity to human estrogens and exhibits high affinity binding to estrogen receptor beta. This article expounded relationship between pathogenesis of perimenopausal syndrome and ...
We tested the mechanisms by which estrogen treatment may alter the impact of a high-fat diet (HED) when given at the time of ovariectomy (OVX) in mice. Female C57BL/6J mice underwent sham operation, OVX, or OVX with estradiol (E2) treatment and were fed an HFD. Hyperinsulinemic-...
differences between the two compared axillary surgery groups, covariables included in propensity score matching were age, race, marital status, grade, T stage, nodal status, estrogen receptor (ER) status, progesterone receptor (PR) status, HER2 status, type of breast surgery, radiation and ...
All groups were scanned twice using MRI: TrM before starting testosterone treatment and TrW before starting antiandrogen (Androkur) and estrogen treatment. The majority of patients participated in a previous study44, in which we reported the sex hormone treatment, plasma level assessment and changes...
Low-dose dietary genistein negates the therapeutic effect of tamoxifen in athymic nude mice The present study examined the effect of dietary genistein, a soy isoflavone, on breast cancer patients who take tamoxifen, an antiestrogen treatment, usin... WG Helferich - 《Carcinogenesis》 被引量: 65...
As the cells in the kidneys do express estrogen receptors (reviewed in [38]), they should be responsive to sex hormones. If this association between the onset of puberty and optimal LiCl responsiveness is correct, the timing results likely indicate that Li modulates puberty-associated changes in...
Recently, it has become possible to reduce estrogen synthesis by inhibiting this aromatase activity using non-steroidal aromatase inhibitors (AIs), such as fadrozole hydrochloride, which is a reversible competitive inhibitor6. Further studies showed that sex change could be induced in many types of ...
However, analytical issues still limit the measurement of estrogen at low but clinically relevant levels [30, 31]. Hereditary breast cancer Factors to be considered regarding recommendation for genetic testing include known mutation in the family, patient or close relative with breast cancer diagnosis ...