(2010) Treatment of Her2-Positive Breast Cancer: What’s on the Horizon. Current Breast Cancer Reports 2 , 42-52 /Windy Dean-Colomb, Francisco J. Esteva. (2010) Treatment of Her2-Positive Breast Cancer: What’s on the Horizon. Current Breast Cancer Reports 2 , 42-52 /...
The therapeutic landscape for HER2-positive metastatic breast cancer has exploded in the last two decades following the initial advent of trastuzumab, a monoclonal antibody. While the first line treatment has remained a combination of dual HER2 blockade with taxane chemotherapy, we now have several ex...
HER2-positive breast cancer is a type of breast cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2), which promotes the growth of cancer cells. Approximately one of every five breast cancers have a gene mutation in the cancer ...
Sara A. Hurvitz, MD, comments on her preferences for treating patients with HER2-positive metastatic breast cancer and shares her strategy for sequencing therapies.
This study evaluated by immunohistochemistry (IHC) immune cell response during neoadjuvant primary systemic therapy (PST) with trastuzumab in patients with HER2-positive primary breast cancer. In all, 23 patients with IHC 3+ primary breast cancer were tr
Treatment of HER2-Positive Metastatic Breast Cancer Following Initial Progression Mayer IA. Treatment of HER2-positive metastatic breast cancer following initial progression. Clin Breast Cancer. 2009; 9 (Suppl 2):S50–57. doi: 10.3816... IA Mayer - 《Clinical Breast Cancer》 被引量: 82发表: 201...
In the first segment, Dr Pegram and colleagues highlight some of the challenges and remaining unmet needs in the management of patients with HER2-positive breast cancer.EP: 1.Examining the Unmet Needs in the Treatment of HER2-Positive Breast Cancer EP: 2.Treating Early-Stage HER2-Positive ...
of neratinib, a tyrosine-kinase inhibitor of human epidermal growth factor-like 2 (HER-2), in the treatment of advanced HER2-positive breast cancer. The... Sharma,Anand,Jayanth,... - 《Advances in Breast Cancer》 被引量: 182发表: 2010年 Improving Treatment of HER2-Positive Cancers: Opport...
Is it important to detect the status of p53 in Her2-positive breast cancer? Breast cancer classification Breast cancer, despite its heterogeneity, can be categorized into five subtypes: luminal type A (estrogen receptor (ER) and (or) PR positive, HER2 negative), luminal type B (ER and (or...
Sara M. Tolaney, MD, discusses the state of adjuvant treatment for patients with HER2-positive breast cancer.