A combination of spironolactone, pioglytopon and metformin, taken in certain quantities, is used for the prevention or treatment of polycystic ovary syndrome, for the prophylaxis or treatment of low ovulation rate relating to hepatic steatosis n adolescent girls or women of childbearing age, as ...
grading, and treatment of schistosomiasis-associated hepatic fibrosis. The multiple regulatory roles of miRNAs, such as promoting or inhibiting the development of liver pathology in murine schistosomiasis are also discussed in depth. Additionally, miRNAs may serve as candidate biomarkers for diagnosing live...
There was no overall correlation between the extent of steatosis and liver size. Hepatic steatosis in childhood malnutrition is not confined to oedematous children: it is frequently present in marasmic and undernourished children. Its extent is not necessarily related to the degree of hepatomegaly ...
Mice with a targeted disruption of the gene encoding SCD1, shown to be resistant to diet-induced weight gain, had increased lipid oxidation and plasma levels of ketone bodies, and reduced levels of plasma insulin and leptin, but developed signs of hepatic steatosis when fed a high-fat diet ...
in addition to hepatic steatosis, the patient is overweight or obese, or has type 2 diabetes, or is lean but shows signs of metabolic syndrome—which in turn is based on the presence of two of seven inclusion criteria—they can receive a diagnosis of MAFLD. As there is no need to elimin...
Additionally, it has been suggested that GGQLD could potentially alleviate non-alcoholic fatty liver disease (NAFLD) and hepatic steatosis by regulating inflammatory factors and oxidative stress through modulation of the NLRP3 signal axis [33]. Our results revealed a decrease in the number of ILCs ...
liver biopsy is currently the gold standard for the definitive diagnosis of NASH and the management of NAFLD worldwide. Liver biopsies enable an accurate evaluation of liver steatosis, cell damage, inflammatory necrosis, and the degree of fibrosis, and histological findings based on liver biopsies ha...
Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity Proc. Natl. Acad. Sci. U. S. A., 104 (2007), pp. 9888-9893 CrossrefView in ScopusGoogle Scholar [70] K. Hosoda, R.E. Hammer, J.A. Richardson, A.G. Baynash, J.C. Cheu...
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH). Expert Opin Investig Drugs. 2020;29:623–32. Article CAS PubMed Google Scholar Sun L, Pang Y, Wang X, Wu Q, Liu H, Liu B, et al. Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and ...
reducing hepatic steatosis, hepatic inflammation, and liver fibrosis, while also improving glucose control. DA-1726 is a novel, dual oxyntomodulin (OXM) analog that functions as a glucagon-like peptide-1 receptor (GLP1R) and glucagon ...