Methods and compositions for treating or ameliorating lower back pain by administering an effective amount of one or more cell types, alone, and/or in combination with a matrix, and/or in combination with growth factors, in order to stimulate lumbar angiogenesis, decrease inflammation, and ...
Degenerative changes in the spine are often referred to those that cause the loss of normal structure and/or function. The intervertebral disc is one structure prone to the degenerative changes associated with wear and tear aging, even misuse (eg, smoking). Long before degenerative disc disease c...
Degenerative disc disease (DDD) is a leading cause of chronic low back pain (LBP), which results in serious disability and causes a substantial global economic burden. Intervertebral disc (IVD) degeneration (IVDD) alters disc structure and spine biomechanics resulting in a positive feedback loop ...
Degenerative disc disease of the cervical spine is a common medical condition in the population with underlying aging, genetic, mechanical and environmental factors. It is characterized with structural collapse, osteophyte formation and loss of the loading function of the intervertebral disc. As a conse...
Degenerative disc disease of the cervical spine is a common medical condition in the population with underlying aging, genetic, mechanical and environmental factors. It is characterized with structural collapse, osteophyte formation and loss of the loading function of the intervertebral disc. As a conse...
In some embodiments, the invention relates to methods of treating degenerative intervertebral disc disease in an individual comprising implanting nucleus pulposus cells into the nucleus pulposus space of a degenerated disc of the individual. Other embodiments of the invention relate to methods of ...
Cervical degenerative disc disease is a condition where age related wear and tear of a cervical spinal disc makes it lose water and become flatter, stiffer, and less capable of absorbing stresses.
Clinical study to evaluate the safety and effectiveness of the Aesculap Activ-L artificial disc in the treatment of degenerative disc disease. BMC Surg 2010; 10:14.Yue JJ, Mo FF. Clinical study to evaluate the safety and effectiveness of the Aesculap Activ-L artificial disc in the treatment ...
A three-dimensional nonlinear finite element analysis of the mechanical behavior of tissue engineered intervertebral discs under complex loads The use of tissue-engineering method holds great promise for treating degenerative disc disease [Gan JC, Ducheyne P, Vresilovic E, Shapiro IM. J Biomed Mat....
total disc replacement (TDR) has been shown in a number of prospective clinical studies to be a viable treatment alternative to anterior cervical discectomy and fusion (ACDF) for the treatment of symptomatic degenerative disc disease. In... Radcliff, Kris E,Davis, Reginald J,Hoffman, Gregory A...