Anemia-Clinical: Sickle cell anemiaRED CELLSBackground Central nervous system (CNS) complications are among the most common, devastating sequelae of sickle cell disease (SCD) occurring throughout the lifespan. Objective These evidence-based guidelines of the American Society of Hematology are intended ...
Sickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and more than 3 million worldwide, is caused by mutations in the βb globin gene that result in sickle hemoglobin production. Sickle hemoglobin polymerization leads to red blood cell sickling, chronic hemolysis...
Genome editing and stem cell therapy pave the path for new treatment of sickle-cell disease Sickle-cell disease (SCD), also known as sickle-cell anemia, is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, the oxyge... MK Randolph,W Zhao - 《Stem Cell ...
Treatment of sickle-cell disease. Br J Haematol 1974; 28: 437-444.Huntsman, R. G. (1974). Treatment of sickle-cell disease. Trans. roy. Soc. trop. Med. Hyg., 68, 80-84.Huntsman, R. et al., " Treatment of Sickle-Cell Disease ", Br. J. Haematol, 1974, Dec., vol. 28(4)...
Sickle cell retinopathy: diagnosis and treatment.###Retinal hamartoma in childhood.###Methotrexate in ocular manifestations of Behcet's disease: a longitudinal study up to 15 years.###Herpetic acute anterior uveitis complicated by retinal vasculitis in an immunocompetent child.###Role of ultra-...
Guideline on the management of acute chest syndrome in sickle cell disease. Br J Haematol. 2015;169(4):492-505.PubMedGoogle ScholarCrossref 22. Martí-Carvajal AJ, Conterno LO, Knight-Madden JM. Antibiotics for treating acute chest syndrome in people with sickle cell disease. Cochrane ...
Sickle cell disease is a hereditary condition that causes red blood cells to be deformed. Sickle cell anemia (sickle cell disease) is a disorder of the blood caused by inherited abnormal hemoglobin (the oxygen-carrying protein within the red blood cells). The abnormal hemoglobin causes distorted ...
摘要: Take-Home Message There is no clear evidence that any one pharmacologic agent or strategy is superior for the acute management of sickle c关键词: Humans Anemia, Sickle Cell Ketorolac Adrenal Cortex Hormones Narcotics Anti-Inflammatory Agents, Non-Steroidal Emergency Service, Hospital Adult ...
To identify disease-related risk factors and psychosocial resistance factors that impact adherence to prescribed treatment in the context of admission to a Hematology Acute Care Unit (HACU) designed to provide acute care for children with sickle cell disease (SCD) presenting with pain or fever. A ...
Most people with sickle cell disease who received a new gene editing treatment saw their pain resolve for at least one year, but longer follow up is needed