Worldwide, the incidence of major depressive disorder (MDD) is increasing annually, resulting in greater economic and social burdens. Moreover, the pathological mechanisms of MDD and the mechanisms underlying the effects of pharmacological treatments for
A method for the treatment and/or prophylaxis of an inflammatory condition of the intestine of a patient, comprises parenteral administration to the patient of an effective amount o
3. The role of Nrf2/ARE signaling pathway in normal intestinal function, IBD and IBD complications 4. Nrf2 activators for the treatment of IBD 5. The potential of gut microbe and microbial metabolite for the treatment of IBD via the Nrf2/ARE pathway 6. Conclusion and future direction Funding...
While scientists are working to better understand the exact cause of IBD, it’s generally believed that the body mistakes normal bacteria in the gut for an enemy. As a result of the body’s natural defenses, this causes chronic inflammation of the digestive tract. In contrast, there are no...
The subject invention pertains to materials and methods for the prevention and treatment of disease conditions associated with oxidative stress or a compromised reducing environment
The Benign tumors grow in size and rarely involve a risk to life. With time, the Cancerous cells spread thus invading other body Organs. This invasion deteriorates the health of an individual and makes the treatment tough. The Cancerous tumors require nutrition to grow which is carried for ...
In severe, refractory cases, biologic therapy is used. The authors reviewed the current literature on the etiology, diagnostic tools, and treatment of uveitis in the pediatric population covering the years 2018–2023, presenting current methods of modern diagnosis and treatment. The reason for ...
Biological samples contain a variety of metabolites that can be used for clinical purposes in the diagnosis of various clinical conditions and many severe disorders. Among sample preparation techniques, the most widely used procedure is solidphase microextraction (SPME), which includes sampling, extractio...
All of these pathways, along with lower levels of glutathione (GSH), are associated with an increase in oxidative stress. The latter in turn causes different alterations in the diabetic retina as a consequence of severe lipid peroxidation, protein oxidation, oxidative DNA damage, induction of ...