TREATMENT FOR ACUTE MYELOID LEUKEMIAMethods of treating acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) are provided, as are compositions and combinations suitable for use in said methods.Hans de HaardNicolas LeupinAdrian Ochsenbein...
which produces blood cells. "Myelogenous" refers to the type of blood cells this leukemia affects. "Chronic" means this cancer is more slowly progressing than other severe forms of leukemia.
said, "Our research highlighted an additional mode of action for the treatment known as eprenetapopt opening up its potential to work in a broader group of acute myeloid leukemia (AML) andmyelodysplastic syndrome(MDS) patients.
Eiring AM, Khorashad JS, Morley K, Deininger MW. Advances in the treatment of chronic myeloid leukemia. BMC Med. 2011;9:99.Eiring AM, Khorashad JS, Morley K, Deininger MW. Advances in the treatment of chronic myeloid leukemia. BMC Med 2011; 9: 99....
None of these patients had a history of preleukemia or had received chemotherapy or radiation therapy for a previous malignancy. Table 1.. Comparability of Patient Groups in Induction Induction Therapy ara-C method No. of patientsAge <60 yr (n = 247)Age >60 yr (n = 105) 5 and 27 and...
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Cytarabine ocfosfate (SPAC) was administered orally to 19 patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). SPAC was administered at doses of 200-300 mg/day for more than 14 days with granulocyte colony-stimulating factor (G-CSF). Four of the 12 patients with ...
acute myeloid leukemiadecitabineelderlyhypomethylationIntroduction: Intensive chemotherapy remains the only therapeutic option that provides a reasonable chance of long-term survival for adults with acute myeloid leukemia (AML), particularly for those younger than 60 years of age. However, the vast majority...
DIAGNOSTIC AND TREATMENT FOR CHRONIC AND ACUTE PHASE MYELOID LEUKEMIADisclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of ...
Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, bu