Mild chronic hepatitis C with steatosis: Which treatment?doi:10.1002/hep.20670EmanueleInternalDurante-MangoniInternalRosaInternalZampinoInternalGiuseppeInternalRuggieroInternalLuigiInternalE.InternalAdinolfiInternalWileyHepatology
grading, and treatment of schistosomiasis-associated hepatic fibrosis. The multiple regulatory roles of miRNAs, such as promoting or inhibiting the development of liver pathology in murine schistosomiasis are also discussed in depth. Additionally, miRNAs may serve as candidate biomarkers for diagnosing live...
Patients with a sustained creatinine clearance between 30 and 49 mL/min should be monitored for hematologic toxicities, which may require a dosage adjustment of lamivudine as an individual component Hepatic Impairment: Dovato is not recommended in patients with severe hepat...
TE has been approved for use in the USA, Europe, and the Asia-Pacific region. It can accurately identify advanced liver fibrosis and early cirrhosis,84,85 but its results are susceptible to liver necroinflammation, cholestasis, and severe steatosis. TE results should be interpreted in combination...
Rare side effects of AZT include potentially life-threatening lactic acidosis (accumulation of lactic acid in body fluids) and hepatic steatosis (accumulation of fat in liver cells), which stem from dysfunctional glucose metabolism by mitochondria in the liver. While AZT is effective in inhibiting ...
Recent cohort studies suggest that InSTI-based ART may be associated with an increased risk of incident cardiovascular disease, new-onset diabetes, hyperglycemia,78-80 elevated blood pressure,80 and de novo hepatic steatosis. These cardiometabolic effects were not observed in other studies, and it ...
identified octopamine as a genetically-determined metabolite, colocalising with a NAFLD-specific QTL. We then evaluated the therapeutic potential of octopamine and demonstrate it improves hepatic steatosis and glucose tolerance independently of obesity, opening avenues for octopamine in the treatment of ...
(or, 4.52; 95% ci, 1.30-15.72; p = .02), possibly associated with hepatic steatosis (etable 3 in the supplement ). folic acid was prescribed for 239 of the 253 patients for whom this information was available (94.5%), with a mean (sd) folic acid dosage of 7.5 (5.8) mg/...
In the neuronal cells we studied whether the autophagy-enhancers lithium, trehalose, rapamycin, and resveratrol and/or the ROS-scavengers [resveratrol, NAC and Mn-Tbap [Mn(III)tetrakis (4-benzoic acid) porphyrin)] can ameliorate neuronal mild mitochondrial-dysfunction. Only lithium (added for the...
Also described herein is treatment of fatty liver (also called hepatic steatosis), including non-alcoholic fatty liver disease. Fatty liver is defined as an excessive accumulation of triglyceride inside the liver cells. For example, in patients with non-alcoholic fatty liver disease, liver contains ...