The therapeutic benefits of many cell types involve paracrine mechanisms. Inspired by the paracrine functions of exosomes and the sustained degradation properties of microcapsules, here we report the therapeutic benefits of exosome-loaded degradable poly
Globally, cardiovascular diseases remain among the leading causes of mortality, highlighting the urgent need for innovative research models. Consequently, the development of accurate models that simulate cardiac function holds significant scientific and
With microvascular angina, you have chest pain but no coronary artery blockage. Instead, it happens because your smallest coronary arteries aren't working the way they should, so your heart doesn't get the blood it needs. The chest pain usually lasts more than 10 minutes. This type is more...
Protein acetylation is required for key cellular processes related to physiology and diseases, such as transcriptional activity, protein stability, enzyme activity, protein‒protein interactions, subcellular localization, and protein‒DNA interactions.172Histone acetylation was first found to modulate gene ...
Ischemic heart diseaseMyocardial perfusionCardiac imagingIntroduction: In 2019, 17.9 million people died from cardiovascular disease, 85% of which were due to acute myocardial infarction (AMI). Post-AMI congestive heart failure is increasing due to microvascular obstruction (MVO). MVO is the blockage ...
Globally, cardiovascular diseases remain among the leading causes of mortality, highlighting the urgent need for innovative research models. Consequently, the development of accurate models that simulate cardiac function holds significant scientific and
Angina (ischemic chest pain) causes include heart disease, coronary artery spasm, and other conditions. Risk factors include high blood pressure, smoking, diabetes, high cholesterol, family history, aging, a sedentary lifestyle, and stimulant use.
Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the committee on rheumatic Fever, endocarditis, and kawasaki disease, council on cardiovascular disease in the young, and the councils on clinical cardiology, stroke, and...
Hypertension affects approximately one third of the world’s adult population and is a major cause of premature death despite considerable advances in pharmacological treatments. Growing evidence supports the use of lifestyle interventions for the preven
Mesenchymal Stem Cells (MSCs) have been studied extensively for the treatment of several retinal diseases. The therapeutic potential of MSCs lies in its ab