Pathogenesis and treatment of macrocytic anemia; information obtained with radioactive vitamin B12. AMA Arch Intern Med. 1956 Nov; 98 (5):541–549.Mc Intyre PA, Sachs MV, Krevans JR. Wonley CL. Pathogenesis and treatment of macrocytic anemia: information obtained with radioactive B,2. Arch...
THE TREATMENT of pernicious anemia with cobalamin is one of medicine's great success stories. However, the usual practice of giving the drug as an intramus... Lederle,A Frank - 《Journal of the American Medical Association》 被引量: 140发表: 1991年 The neurology of folic acid deficiency. ...
B12 deficiency is associated with a particular type of anemia. This type, called macrocytic anemia, can be identified with a blood smear.10 With this type of anemia, RBCs are large and may have varied shapes and sizes. At-Home Vitamin Deficiency Tests Imaging and Specialized Tests Other ...
He had macrocytic anemia (haemoglobin: 3.7 mmol/l) and the tongue ... PJ Zuidema - 《Nederlands Tijdschrift Voor Geneeskunde》 被引量: 5发表: 1996年 The treatment of pernicious anemia In 1952, after the identification of vitamin B12 as the anti-pernicious-anaemia principle of liver, the U....
Overall, vitamin B12 deficiency is treatable and can lead to serious neurological sequelae if left untreated, so it is important to consider vitamin B12 deficiency as a potential cause in patients with unexplained epilepsy, especially when accompanied by macrocytic anemia [85]. Long-term use of ant...
Overall, vitamin B12 deficiency is treatable and can lead to serious neurological sequelae if left untreated, so it is important to consider vitamin B12 deficiency as a potential cause in patients with unexplained epilepsy, especially when accompanied by macrocytic anemia [85]. Long-term use of ant...
Experimental production of a nutritional macrocytic anemia in swine bone marrow with an increase in immature nucleated red cells which resemble the megaloblasts seen in the bone marrow of patients with pernicious anemia.3... JG Palmer,GE Cartwright,MM Wintrobe - 《American Journal of Medicine》 被...
If the MCV is high, then it is calledmacrocytic anemia (large red blood cell volume). Looking at each of the components of acomplete blood count(CBC), especially the MCV, a physician can gather clues as to what could be the most common reason for anemia in each patient. ...
Treatment of tropical sprue with folate and B12cures the macrocytic anemia and the accompanying glossitis, and often results in increased appetite and weight gain. However, even prolonged treatment with these vitamins fails to restore villus atrophy, and malabsorption usually persists. The benefit of ...
are overexpressed. Zbtb7a-/-mice models are embryonic lethal due to anemia, whereas the conditional knockout of Zbtb7a in adult mice leads to mild macrocytic anemia following inefficient terminal erythropoiesis [48,65]. CRISPR/Cas9-mediated knockout of LRF in an erythroid cell line resulted in ...