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The present invention relates to the finding that receptors for the neurotransmitter 5-HT of the 5-HT2B class are located on the human colon, and that their activation potentiates neuronally-mediated responses, and are thus causative in the abnormal motility and pain associated with IBS. The ...
Medications that treat irritable bowel syndrome (IBS) include antidiarrheal drugs, laxatives and stool softeners, and probiotic supplements. The best medication to use for IBS depends on your symptoms, which include abdominal pain and changes in bowel movement patterns. You might have diarrhea, consti...
Antispasmodics can help with pain—these are generally anticholinergic drugs. Narcotics should never be used, secondary to their propensity to decrease bowel motility. For some patients with severe and refractory symptoms, especially pain, low-dose tricyclic antidepressants can be very effective. Probioti...
The data are inconsistent, with some trials showing benefit with respect to abdominal pain, stool frequency, and global IBS symptoms, and other trials showing these agents to be no better than placebo. In addition, there is potential for these agents to cause abdominal discomfort and bloating. ...
Dr. Stephen Wangen, our founder and Medical Director, had IBS. And since 2005 we've been helping people solve challenging cases of these symptoms: Abdominal pain Urgency Diarrhea Constipation Bloating Gas Don't let other doctors convince you that it's hopeless. Get your life back and start li...
The pathophysiologic basis for IBS has not been fully elucidated. It has been shown that patients with IBS have an exaggerated response to GI contents, including greater motility of the sigmoid colon and a lower threshold to visceral pain compared with controls.[2]It is thought that neurotransmitt...
IBS must only be diagnosed after every other possible causes of the type of pain that you have has been excluded. So it is important not to self diagnose and treat yourself for IBS, just in case it is something else. See your doctor. ...
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