The present invention provides a pharmaceutical composition for use in prevention or treatment of a human rhinovirus (HRV) infection. The composition comprises an aldohexose, wherein the hydroxyl group at carbon 2 of the aldohexose is replaced by any one of H, F, CI, Br, I, SH, Me, ...
Rhinoviruses (RVs) are members of the Picornaviridae family, which includes the human pathogens enterovirus and hepatovirus (notably, hepatitis A virus). More than 100 different subtypes exist in 3 major groups, categorized according to receptor specific
PURPOSE: An antivirus composition containing lauric acid as an active ingredient is provided to ensure the activity for suppressing proliferation to rhino virus, coxsackie virus, and enterovirus.;CONSTITUTION: An antivirus composition contains lauric acid of the chemical formula 1 as an active ingredien...
Pleconaril treatment of enterovirus and rhinovirus infections These pathogens are responsible for a wide spectrum of human disease, ranging from the common cold and nonspecific febrile illnesses to myocarditis, meningitis and, in certain patient populations, potentially life-threatening infections. ... HA...
CARVs, including orthymyxo- (influenza virus), paramyxo- (RSV, PIV, HMPV), picorna- (human rhinovirus [HRhV]), coronaviruses (HCoVs), human bocavirus (HBoV), and polyomaviruses, are important pathogens of respiratory tract infections in the recipients of allo-HSCT, [26]. Significant ...
Human Rhinovirus Type II HSA: Human Serum Albumin ICD: Immunogenic Cell Death IRES: Internal Ribosome Entry Site LDCT: Low-dose Computed Tomography LDI-TOF MS: Laser Desorption Ionization Time-of-Flight Mass Spectrometry LNPs: Lipid Nanoparticles MPR: Major Pathologic Response MRI: Magne...
Background.Recent updates of human immunodeficiency virus (HIV) treatment guidelines have raised the CD4+ cell count thresholds for antiretroviral therapy initiation from 350 to 500 cells/mm(3) in the United States and from 200 to 350 cells/mm(3) in mid- and low-income countries. Robust data...
Zinc is a multifunctional ion endowed with antibacterial and antiviral activities, regenerative potential, and biological functionality [82,83]. The antiviral activity of zinc dates back to 1974, when its potential against the human rhinovirus was first reported [84]. Although the antiviral mechanism...
It is also an enveloped virus surrounded by hemagglutinin and neuraminidase glycoproteins, being the first one responsible for host cell recognition [7]. In the case of Human rhinovirus (HRVs), its size is smaller (∼30 nm) and, unlike the coronavirus, it has a non-enveloped structure ...
Zinc is a multifunctional ion endowed with antibacterial and antiviral activities, regenerative potential, and biological functionality [82,83]. The antiviral activity of zinc dates back to 1974, when its potential against the human rhinovirus was first reported [84]. Although the antiviral mechanism...