HPV+ non-smoking-associated oropharyngeal carcinoma is unusually responsive to conventional chemoradiation and less frequently results in distant metastasis. As these "low-risk" patients are often cured by standard treatments and experience lengthier survival than other head and neck cancer patients, the ...
Increasingly, squamous cell carcinoma of the oropharynx (OPSCC) is attributable to transformation resulting from high-risk human papillomavirus (HPV) infec... JR Kelly,ZA Husain,B Burtness - 《European Journal of Cancer》 被引量: 14发表: 2016年 Treatment De-Intensification for Locally Advanced HPV...
Starting from the early use of general anesthesia in surgical resections in the mid-1800s, to Wilhelm Conrad Röntgen’s invention of X-rays at the end of the 19th century,3 which initiated the era of combining radiation with surgery for cancer treatment, to the breakthroughs in chemotherapy...
HPV genotyping has potentially valuable applications in triage of low-grade abnormal cervical cytology, assessment of prognosis and followup of cervical intraepithelial neoplasia, and in treatment strategies for invasive cervical cancer. It is known that during the development of cervical cancer associated...
HPV infection is the primary cause of cervical intraepithelial neoplasia (CIN), with persistent high-risk HPV infection being the leading factor in the development of cervical cancer. In addition to the application of large loop excision of the transformation zone (LLETZ) for the treatment of cervi...
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with advanced age and immunosuppression. Over the past decade, an association has been discovered between MCC and either integration of the Merkel cell polyomavirus, which likely drives tumorigenesis, or somatic mutations owing...
Cancer is a disease characterized by the uncontrolled multiplication of abnormal cells in the body. There are numerous types of cancers, with certain types being major causes of sickness and death worldwide.
the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other mali...
Gardasil human papillomavirus vaccineGardasil, the trade name of a human papillomavirus (HPV) vaccine, protects against four different types of HPV that are responsible for cervical cancer and genital warts. Vaccines againsthuman papillomavirus(HPV) are made from viruslike particles (VLPs), which are...
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